Chemistry Heterocyclic Building Blocks Benzoxazoles
Benzoxazole is an organic compound with an aromatic benzene-fused oxazole ring structure, a molecular formula of C7H5NO, and an odor resembling pyridine.
Benzoxazole, a heterocyclic compound, serves as a fundamental building block for synthesizing larger bioactive structures in research. Its stability is attributed to its aromaticity, yet it contains reactive sites due to its heterocyclic nature, which enable functionalization.
Benzoxazoles are a well-known group of antifungal agents that exhibit antioxidant, antiallergic, antitumoral, and antiparasitic activities.
An aryl ring is fused with the "d" position of an oxazole group, creating a bicyclic structure, which characterizes benzoxazole as a significant type of heterocycle.
After reacting with diverse electrophiles and electron-rich species, benzoxazoles, which are heteroaromatic compounds, can yield a multitude of products.
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2-(tert-Butyl)benzo[d]oxazol-6-amine
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6-Bromo-2-cyclopropyl-5-methylbenzo[d]oxazole
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3-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazole-6-sulfonyl chloride
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(4-(Benzo[d]oxazol-2-yl)phenyl)boronic acid
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2-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazole
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tert-Butyl (2-((5-chlorobenzo[d]oxazol-2-yl)(3-oxobutyl)amino)ethyl)carbamate