Home Life Science Inhibitors/Agonists Stem Cells CREB
The transcription factor CREB is primarily recognized for its participation in learning and memory. Nevertheless, emerging evidence indicates that CREB activity assumes diverse roles—sometimes beneficial, sometimes detrimental—depending on the specific brain region. The initiation of CREB in the hippocampus due to antidepressant treatments may play a role in their therapeutic effectiveness. In contrast, the activation of CREB in the nucleus accumbens and various other regions by drugs of abuse or stress is implicated in certain aspects of drug addiction, as well as depressive and anxiety-like behaviors.
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