DNA/RNA synthesis enzymes include DNA polymerase, RNA polymerase, etc. There are numerous family members, such as DNA polymerase including α, β, γ, δ, etc. Their structure typically consists of a catalytic domain and a DNA/RNA binding domain. They are located in the cell nucleus or cytoplasm, participating in DNA/RNA replication and transcription, regulating gene expression, and protein synthesis. Involved in biological reactions such as cell cycle regulation, DNA repair, and transcriptional control. Gene expression is influenced by cell type and environment, and mutations can lead to changes in enzyme activity and specificity, affecting cell function and disease development.