Home Chemistry Organic Building Blocks Fluorinated Building Blocks Ethyl 2-Fluorobenzoate
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—COOC2H5).
Metalation Reactions: Fluorobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Fischer Esterification: Ethyl benzoate can be synthesized through Fischer esterification, a reaction between benzoic acid and ethanol in the presence of an acid catalyst, usually sulfuric acid (H2SO4): C6H5COOH + C2H5OH → C6H5COOC2H5 + H2O
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4-Ethoxycarbonyl-3-fluorophenylboronic acid
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(3-Ethoxycarbonyl-4-fluorophenyl)boronic acid
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(3-(Ethoxycarbonyl)-2-fluorophenyl)boronic acid
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