Home Chemistry Organic Building Blocks Iodides Methyl 3-Iodo-4-Methylbenzoate
These compounds have the same murcko framework: benzene,and at least 3 kinds of functional groups( —I,—CH3,—COOCH3).
Metalation Reactions: Iodobenzene can undergo metalation reactions, where a metal species (such as an organolithium or organomagnesium compound) replaces a hydrogen atom on the benzene ring. These metalated intermediates can then be used in various synthetic transformations.
Halogenation: Toluene can undergo halogenation reactions with halogens (such as chlorine or bromine) in the presence of a catalyst or under UV light. The hydrogen atoms on the benzene ring can be replaced by halogen atoms, resulting in the formation of mono-, di-, or polyhalogenated derivatives of toluene.
Fischer Esterification: Methyl benzoate can be synthesized through Fischer esterification, where benzoic acid reacts with methanol in the presence of an acid catalyst, typically sulfuric acid. This reaction forms the ester bond and releases water as a byproduct.
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2-CHloro-5-iodo-4-methyl-benzoic acid methyl ester
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Methyl 2-fluoro-5-iodo-4-methylbenzoate
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