Home Chemistry Heterocyclic Building Blocks Piperidines Methyl Piperidine-3-Carboxylate
Ester Hydrolysis: Methyl piperidine-3-carboxylate can undergo hydrolysis in the presence of water and acid or base to yield piperidine-3-carboxylic acid and methanol.
Nucleophilic Substitution: The ester group can undergo nucleophilic substitution reactions with various nucleophiles, leading to the formation of substituted piperidine-3-carboxylates.
Reduction: The carbonyl group of the ester can be reduced to the corresponding alcohols using reducing agents such as lithium aluminum hydride or sodium borohydride.
Amide Formation: The carboxylate group can react with amines to form amides.
Decarboxylation: Under certain conditions, such as heating or treatment with specific reagents, decarboxylation may occur, leading to the loss of the carboxyl group and formation of the corresponding amine.
Esterification: The carboxylate group can react with alcohols or acid derivatives to form esters through esterification reactions.
Ring-opening Reactions: The piperidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
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Methyl piperidine-3-carboxylate hydrochloride
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cis-Methyl 6-methylpiperidine-3-carboxylate hydrochloride
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(3R,6S)-Methyl 6-methylpiperidine-3-carboxylate
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(R)-Methyl piperidine-3-carboxylate hydrochloride
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(S)-3-Piperidinecarboxylic acid methyl ester HCl
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(S)-1-tert-Butyl 3-methyl piperidine-1,3-dicarboxylate
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1-(tert-Butyl) 3-methyl (R)-piperidine-1,3-dicarboxylate
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trans-Methyl 6-methylpiperidine-3-carboxylate hydrochloride
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1-tert-Butyl 3-methyl 4-methylpiperidine-1,3-dicarboxylate
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