Chemistry Heterocyclic Building Blocks Pyridines 2,4-dichloro-6-methylpyridine
Substitution Reactions: The chlorine atoms on the pyridine ring can be replaced by other nucleophiles in substitution reactions. For example, nucleophilic substitution could occur with a strong nucleophile displacing one or both chlorine atoms.
Addition Reactions: The double bond in the pyridine ring can undergo addition reactions with appropriate reagents. This could lead to the formation of new functional groups or ring-opening reactions.
Oxidation Reactions: The methyl group on the pyridine ring can be oxidized under appropriate conditions, leading to the formation of carboxylic acids or ketones.
Reduction Reactions: Conversely, the compound could undergo reduction reactions, where the chloro groups or the pyridine ring itself could be reduced to corresponding products.
Nucleophilic Aromatic Substitution: The electron-deficient pyridine ring can undergo nucleophilic aromatic substitution (SNAr) reactions, where a nucleophile replaces one of the chloro groups on the ring.
Metalation Reactions: The compound could react with strong bases or organometallic compounds, leading to metalation of the pyridine ring or other functional groups present.
Alkylation/Acylation Reactions: The pyridine nitrogen could undergo alkylation or acylation reactions, leading to the introduction of alkyl or acyl groups onto the ring.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
click to sign in and save
Ethyl 2,4-dichloro-6-methyl-3-pyridinecarboxylate
click to sign in and save
Methyl 4,6-dichloro-2-methylnicotinate