Alternatived Products of [ 1005009-95-9 ]
Product Details of [ 1005009-95-9 ]
CAS No. : | 1005009-95-9 |
MDL No. : | MFCD22494883 |
Formula : |
C16H25BO4
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
292.18
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 1005009-95-9 ]
Application In Synthesis of [ 1005009-95-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1005009-95-9 ]
- 1
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[ 53207-08-2 ]
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[ 73183-34-3 ]
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[ 1005009-95-9 ]
Yield | Reaction Conditions | Operation in experiment |
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With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 90 - 100℃; |
Into a four-necked flask, 408 mmol of 1,2-diethoxy-4-bromobenzene (II) and 2400 mL of dioxane were added.Add 1.223 mol of potassium acetate under stirring.Double-linked pinacol borate 788mmol, Pd(dppf)Cl221mmol,The temperature is raised to 90-100 C, and the reaction is kept for 3 to 5 hours to 1,2-diethoxy-4-bromobenzene (II). Cool down to room temperature,A solution of 383 mmol of ethyl bromoacetate dissolved in 800 mL of dioxane and a solution of 1.95 mol of potassium phosphate dissolved in 640 mL of water were added.The temperature is raised to 90 to 100 C, and the reaction is kept for 4 to 6 hours.After the reaction is completed, most of the dioxane is distilled off under reduced pressure.Add 3 L of dichloromethane. Filtered, the filtrate is allowed to stand,Divide the water layer. The organic layer was washed 3 times with water,600mL each time. Evaporated to dryness under reduced pressure to give a pale yellow semi-solid oil, i.e., ethyl 3,4-diethoxy-benzene (III) 258mmol, 63.2% molar yield. |