Alternatived Products of [ 100874-09-7 ]
Product Details of [ 100874-09-7 ]
CAS No. : | 100874-09-7 |
MDL No. : | MFCD00446027 |
Formula : |
C14H10BrNO2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
304.14
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 100874-09-7 ]
Signal Word: | |
Class: | N/A |
Precautionary Statements: | |
UN#: | N/A |
Hazard Statements: | |
Packing Group: | N/A |
Application In Synthesis of [ 100874-09-7 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 100874-09-7 ]
- 1
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[ 74-96-4 ]
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[ 52559-36-1 ]
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[ 100874-09-7 ]
Yield | Reaction Conditions | Operation in experiment |
65.3% |
Stage #1: ethyl bromide; 4-bromonaphthalene-1,8-dicarboximide In N,N-dimethyl-formamide at 70℃; for 0.5h;
Stage #2: With potassium carbonate In N,N-dimethyl-formamide |
3 Example 3, Preparation of Naphthalimide Derivatives IX-1
In a 100 mL round bottom flask, intermediate VIII (2.76 g, 10 mmol), bromoethane (2.18 g, 20 mmol) was added in 15 mL of DMF as organic solvent. The mixture was stirred at 70 ° C. After half an hour, potassium carbonate (4.15 g, 30 mmol) was added to continue the reaction. TLC was followed until the reaction was completed. The mixture was cooled to room temperature (18-25 ° C) and concentrated by filtration. The residue was purified by column chromatography and dried to give 1.99 g of Compound IX-1 in a yield of 65.3%. Yellow powder. |
- 2
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[ 100874-09-7 ]
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[ 32407-11-7 ]
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C21H16Cl2N2O3
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
86% |
With potassium <i>tert</i>-butylate; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene In toluene at 110℃; for 12h; Inert atmosphere; Sealed tube; |
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Reference:
[1]Ungati, Harinarayana; Govindaraj, Vijayakumar; Mugesh, Govindasamy
[Angewandte Chemie - International Edition, 2018, vol. 57, # 29, p. 8989 - 8993][Angew. Chem., 2018, vol. 130, # 29, p. 9127 - 9131,5]