Alternatived Products of [ 1044559-74-1 ]
Product Details of [ 1044559-74-1 ]
CAS No. : | 1044559-74-1 |
MDL No. : | MFCD12498709 |
Formula : |
C18H15ClN2O2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
326.78
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 1044559-74-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 1044559-74-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1044559-74-1 ]
- 1
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[ 3740-92-9 ]
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[ 105-13-5 ]
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[ 1044559-74-1 ]
Yield | Reaction Conditions | Operation in experiment |
100% |
With sodium hydride; In tetrahydrofuran; at 0℃; for 1.5h; |
Step b: 4-Chloro-6-(4-methoxybenzyloxy)-2-phenylpyrimidine (6b); NaH (60percent) (469 mg, 11.73 mmol) was added in portions to a stirred solution of <strong>[3740-92-9]4,6-dichloro-2-phenyl-pyrimidine</strong> (2.2 g, 9.78 mmol) and 4-methoxy benzyl alcohol (1.62 mg, 11.73 mmol) in dry THF (55 ml) at 00C. After 1.5 h, NaHCO3 (aq) was added. Some solvent was evaporated and the residue was extracted with DCM, dried (MgSO4), filtered and evaporated to give the title compound, (3.19g, 100percent), MS (M+H)+327. |