Alternatived Products of [ 109911-37-7 ]
Product Details of [ 109911-37-7 ]
CAS No. : | 109911-37-7 |
MDL No. : | |
Formula : |
C6H6BrNO2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
204.02
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 109911-37-7 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 109911-37-7 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 109911-37-7 ]
- 1
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[ 19355-04-5 ]
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[ 109911-37-7 ]
Yield | Reaction Conditions | Operation in experiment |
89% |
With Acetyl bromide; acetic acid at 80℃; for 1h; Inert atmosphere; |
212.3
[00661] Step 3: To a solution of 3-methoxy-4-nitro-pyridine 1-oxide (3.0 g, 17.6 mmol) in acetic AcOH (30 mL) was added AcBr (65.0 g, 529 mmol). The resulting mixture was stirred at 80 °C for 1 hr. Then the reaction mixture was neutralized with saturated aqueous NaOH till pH = 8. The aqueous phase was extrated with EtOAc (60 mL x4). The extracts were washed with brine (60 mL x4), dried over Na2S04 and concentrated to afford 4-bromo-3-methoxy-pyridine 1 -oxide (3.2 g, yield: 89%) as a yellow solid, which was used for next step without further purification. MS: m/z 203.9 (M+H+). |
77% |
With Acetyl bromide |
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