Alternatived Products of [ 1210047-55-4 ]
Product Details of [ 1210047-55-4 ]
CAS No. : | 1210047-55-4 |
MDL No. : | MFCD16987753 |
Formula : |
C8H4BrFN2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
227.03
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 1210047-55-4 ]
Application In Synthesis of [ 1210047-55-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 1210047-55-4 ]
- 1
-
[ 153505-37-4 ]
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trans-1,4-dioxane-2,3-diol
[ No CAS ]
-
[ 1210047-55-4 ]
Yield | Reaction Conditions | Operation in experiment |
81% |
In ethanol; at 20℃; for 2h; |
1.300 g (16.095 mmol) of 4-bromo-5-fluorobenzene-l,2-diamine (described in WO 2008/021851, p. 75-76) was dissolved in 160 ml ethanol and 1.933 g (16.095 mmol) /r°/s-2,3-dihydroxy-l,4- dioxane was added. It was stirred for 2 h at room temperature and the reaction mixture was concentrated to 3/4 by evaporation in a rotary evaporator. The resultant precipitate was filtered off and dried under high vacuum. We obtained 2.950 g (81% of theor.) of the target compound.LC-MS (method 4): R, = 1.00 min; MS (EIpos): m/z = 227 [M+H]+. 1H-NMR (400 MHz, DMSO-D6): delta [ppm] = 8.11 (d, IH), 8.58 (d, IH), 8.98-9.03 (m, 2H). |