Alternatived Products of [ 133447-23-1 ]
Product Details of [ 133447-23-1 ]
CAS No. : | 133447-23-1 |
MDL No. : | |
Formula : |
C10H14O2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
166.22
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 133447-23-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 133447-23-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 133447-23-1 ]
- 1
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[ 5266-85-3 ]
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[ 133447-23-1 ]
Yield | Reaction Conditions | Operation in experiment |
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Step 1: 2-Isopropyl-6-methylbenzene-1,4-diol To a 55 C. solution of potassium dichromate (40 g) in water (400 mL) was added a solution (60 C.) of <strong>[5266-85-3]2-isopropyl-6-methylaniline</strong> (31 mL) and conc. sulfuric acid (65 mL) in water (400 mL). The solution was stirred for 1 hour then extracted with dichloromethane. After removing the solvent, the residue was dissolved in acetone (300 mL) and refluxed with water (150 mL) and conc. sulfuric acid (15 mL) for 3 hours. The acetone was removed and the mixture was extracted with ethyl acetate. Evaporation and a quick flash column (silica gel, hexane-dichloromethane 1:1) gave a quinine residue that was dissolved in ethyl acetate and shaken with excess of sodium hydrosulfite water solution. Evaporation gave 9.5 g of 2-Isopropyl-6-methylbenzene-1,4-diol. |