1403746-83-7|3-Bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid hydrochloride| Ambeed

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Yield	Reaction Conditions	Operation in experiment
100%	With hydrogenchloride; In 1,4-dioxane; at 90.0℃;	Step 2. 3-bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid hydrochloride To a solution of <strong>[1190312-64-1]methyl 3-bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylate</strong> (2.90 g, 11.4 mmol) in 1,4-dioxane (30 mL) was added 6 N aqueous hydrochloric acid (18.9 mL, 114 mmol). The reaction was heated to 90 C. and stirred overnight. The reaction was cooled to room temperature and concentrated to dryness to afford the title compound (2.76 g, quantitative). 1H NMR (400 MHz, DMSO-d6, delta): 12.31 (br. s., 1H), 8.91 (d, J=1.8 Hz, 1 H), 8.37 (s, 1H), 8.14 (d, J=1.6 Hz, 1H).

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Ghs Hazard Statements

Physical hazards
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H200	Unstable explosive
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Health hazards
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Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

CAS No. :	1403746-83-7	MDL No. :
Formula :	C₈H₆BrClN₂O₂	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	-
M.W :	277.50	Pubchem ID :	-
Synonyms :

Signal Word:		Class:
Precautionary Statements:		UN#:
Hazard Statements:		Packing Group:

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[ 1403746-83-7 ] Synthesis Path-Downstream 1~1

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