Alternatived Products of [ 162100-99-4 ]
Product Details of [ 162100-99-4 ]
CAS No. : | 162100-99-4 |
MDL No. : | MFCD20269640 |
Formula : |
C9H10BrN
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
212.09
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 162100-99-4 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 162100-99-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 162100-99-4 ]
- 1
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[ 248602-16-6 ]
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[ 162100-99-4 ]
Yield | Reaction Conditions | Operation in experiment |
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With sodium cyanoborohydride; acetic acid; at -10 - 20℃; |
Steps 1-3 A solution of <strong>[248602-16-6]6-bromo-5-methylindole</strong> (1.00 g, 4.75 mmol) in AcOH (150 mL) was treated with NaBH3CN (0.897 g, 14.3 mmol) while maintaining a temperature of -10 C. The mixture was then stirred at RT overnight and concentrated. The resulting residue was treated with aqueous K2CO3, and extracted with DCM (3×100 mL). The combined organic layers were dried over MgSO4, concentrated and purified by column chromatography (0-75% EtOAc/hexanes) to afford 6-bromo-5-methylindoline (13A, 716 mg). |