Alternatived Products of [ 188532-26-5 ]
Product Details of [ 188532-26-5 ]
CAS No. : | 188532-26-5 |
MDL No. : | MFCD32671359 |
Formula : |
C18H25NO3S
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | QDYYSPGKYXWGSL-UHFFFAOYSA-N |
M.W : |
335.46
|
Pubchem ID : | 9819104 |
Synonyms : |
|
Chemical Name : | 5-(3,5-Di-tert-butyl-4-hydroxybenzyl)thiazolidine-2,4-dione |
Safety of [ 188532-26-5 ]
Application In Synthesis of [ 188532-26-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 188532-26-5 ]
- 1
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[ 50-00-0 ]
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[ 188532-26-5 ]
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[ 107902-67-0 ]
Yield | Reaction Conditions | Operation in experiment |
|
With ammonia In methanol; n-heptane; ethyl acetate |
2.C C.
C. 5-[3,5-bis-(1,1-dimethylethyl)-4-hydroxyphenyl}methyl-4-thiazolidinone To 2.78 g (9.2 mmol) of 5-[3,5-bis(1,1-dimethylethyl]-4-hydroxyphenyl]-methyl-2,4-thiazolidinedione in a pressure tube, 13 ml of methanol was added. The mixture was cooled to 0-5° C. and 2.2 g (130 mmol) of ammonia and 0.76 ml (10 mmol) of formalin (aqueous formaldehyde) was added. The tube was sealed and heated to 80° C., while stirring, for 20 hours. The mixture was cooled to ambient temperature, then subjected to flash column chromatography using 1:1 ethyl acetate:heptane. Analysis by 1 H-NMR and HPLC indicated 60% of the sample was the title compound. |