Alternatived Products of [ 201996-37-4 ]
Product Details of [ 201996-37-4 ]
CAS No. : | 201996-37-4 |
MDL No. : | MFCD00209704 |
Formula : |
13C3H3N3O3
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
132.05
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 201996-37-4 ]
Application In Synthesis of [ 201996-37-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 201996-37-4 ]
- 1
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[ 58069-82-2 ]
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[ 201996-37-4 ]
Yield | Reaction Conditions | Operation in experiment |
88.4% |
In sulfolane at 205℃; for 2h; |
|
87% |
In sulfolane; cyclohexanol at 50 - 200℃; |
|
|
With sulfolane; cyclohexanol at 60 - 210℃; for 3h; |
4.4.1. Synthesis of 13C3-Cyanuric Acid
A mixture of sulfolane (12 g, 0.100 mol) and cyclohexanol (4 g, 0.040 mol) was stirred in a 50 mLthree-neck flask equipped with a reflux condenser. When the temperature reached 60 °C, 13C-urea (4 g,0.067 mol) was added into the flask. Under negative pressure, the reaction mixture was refluxed for3 h at 200-210 °C until the system did not generate ammonia any longer. The reaction system was cooled 50 °C, and the precipitate was filtered and washed with ethyl alcohol. The final product wasdried in an oven at 60 °C for 2 h. A total of 2.5 g (0.019 mol) of crude product was obtained, and theyield was 81.8% (Scheme 1). |
Reference:
[1]Location in patent: experimental part
Luo, Yong; Zhang, Liya; Yang, Weicheng; Liu, Weixia; Lu, Weijing; Li, Meihua
[Journal of labelled compounds and radiopharmaceuticals, 2011, vol. 54, # 4, p. 171 - 172]
[2]Chen, Shuo; Lin, Dejie; Jiang, Zhifu; Zhao, Jian; Gao, Beibei; Mei, Xiangdong; Ning, Jun; She, Dongmei
[Journal of labelled compounds and radiopharmaceuticals, 2013, vol. 56, # 5, p. 305 - 306]
[3]Song, Yan; Guo, Yangzhen; Zhang, Xia; Yang, Yue; Chen, Shuo; She, Gaimei; She, Dongmei
[Molecules, 2016, vol. 21, # 1]