Home Cart 0 Sign in  

[ CAS No. 21900-48-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 21900-48-1
Chemical Structure| 21900-48-1
Structure of 21900-48-1 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 21900-48-1 ]

Related Doc. of [ 21900-48-1 ]

Alternatived Products of [ 21900-48-1 ]

Product Details of [ 21900-48-1 ]

CAS No. :21900-48-1 MDL No. :MFCD08543466
Formula : C8H6BrClO Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 233.49 Pubchem ID :-
Synonyms :

Safety of [ 21900-48-1 ]

Signal Word:Danger Class:8
Precautionary Statements:P264-P270-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P403+P233-P501 UN#:3265
Hazard Statements:H302-H314 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 21900-48-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 21900-48-1 ]
  • Downstream synthetic route of [ 21900-48-1 ]

[ 21900-48-1 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 21900-48-1 ]
  • [ 52780-15-1 ]
Reference: [1] Patent: EP2878594, 2015, A1,
  • 2
  • [ 67-56-1 ]
  • [ 21900-48-1 ]
  • [ 99548-54-6 ]
YieldReaction ConditionsOperation in experiment
957 mg With triethylamine In dichloromethane at 20℃; Cooling with ice To an ice-cooled solution of Compound I (1.0 g) in methylene chloride (9.0mL) were added dropwise DMF (20 μL) and thionyl chloride (480 μL), and then the mixture was stirred at room temperature for 3 hours, and the reaction mixture was concentrated under reduced pressure. The resulting residue was dissolved in methylene chloride (9.3 mL), and the mixture was ice-cooled, and then thereto were added dropwise triethylamine (1.3 mL) and methanol (4.6 mL). The mixture was stirred at room temperature overnight, and then the reaction mixture was concentrated under reduced pressure. To the residue was added water, and then the mixture was extracted with ethyl acetate. The organic layer was washed with brine, and then dried over sodium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 100/0 to 85/15) to give Compound II (957 mg).
Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 17, p. 4505 - 4509
[2] Patent: EP2612848, 2013, A1, . Location in patent: Paragraph 0311; 0312; 0313
  • 3
  • [ 21900-48-1 ]
  • [ 337536-15-9 ]
Reference: [1] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 17, p. 4505 - 4509
Same Skeleton Products
Historical Records