Alternatived Products of [ 2244454-05-3 ]
Product Details of [ 2244454-05-3 ]
CAS No. : | 2244454-05-3 |
MDL No. : | MFCD32868776 |
Formula : |
C11H9Cl2NO2
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
258.10
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 2244454-05-3 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 2244454-05-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 2244454-05-3 ]
- 1
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[ 170879-71-7 ]
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[ 2244454-05-3 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 4 steps
1: sodium / methanol; dichloromethane / -78 - 20 °C
2: o-xylene / 0.83 h / 130 °C
3: potassium carbonate / N,N-dimethyl-formamide / 1 h / 60 °C
4: sodium hydroxide; water / methanol / 1 h / 65 °C |
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Reference:
[1]Arnhof, Heribert; Bader, Gerd; Bruchhaus, Jens; Burkard, Michelle; Ciftci, Tuncay; Dahmann, Georg; Du, Alicia; Ettmayer, Peter; Fett, Thomas N.; Garavel, Géraldine; Gerstberger, Thomas; Haering, Daniela; Harrer, Christoph; Hofbauer, Karin S.; Kessler, Dirk; Kousek, Roland; Li, Dongyang; Li, Yali; Lv, Xiaobing; Martinelli, Paola; Mayer, Moriz; McConnell, Darryl B.; Mischerikow, Nikolai; Mitzner, Sophie; Pearson, Mark; Peric-Simov, Biljana; Quant, Jens; Rinnenthal, Joerg; Rumpel, Klaus; Savarese, Fabio; Scherbantin, Yvonne; Schnitzer, Renate; Scholz, Guido; Schrenk, Andreas; Sharps, Bernadette; Sommergruber, Wolfgang; Treu, Matthias; Weinstabl, Harald; Wolkerstorfer, Bernhard; Zahn, Stephan K.; Zhang, Xuechun; Zoephel, Andreas
[Journal of Medicinal Chemistry, 2019]