[ CAS No. 28282-25-9 ] {[proInfo.proName]}

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Quality Control of [ 28282-25-9 ]

COA NMR CNMR HPLC LC-MS

Related Doc. of [ 28282-25-9 ]

SDS Specification

Alternatived Products of [ 28282-25-9 ]

Product Details of [ 28282-25-9 ]

CAS No. :	28282-25-9	MDL No. :
Formula :	C₃₀H₄₆O₃	Boiling Point :	-
Linear Structure Formula :	-	InChI Key :	-
M.W :	454.68	Pubchem ID :	-
Synonyms :	Elemadienonic Acid;3-Oxotirucallenoic Acid;3-oxo Tirucallic Acid;Beta-Elemonic acid	Chemical Name :	Beta-elemonicacid

Calculated chemistry of [ 28282-25-9 ]

Physicochemical Properties

Num. heavy atoms :	33
Num. arom. heavy atoms :	0
Fraction Csp3 :	0.8
Num. rotatable bonds :	5
Num. H-bond acceptors :	3.0
Num. H-bond donors :	1.0
Molar Refractivity :	137.85
TPSA :	54.37 Å²

Pharmacokinetics

GI absorption :	Low
BBB permeant :	No
P-gp substrate :	Yes
CYP1A2 inhibitor :	No
CYP2C19 inhibitor :	No
CYP2C9 inhibitor :	Yes
CYP2D6 inhibitor :	No
CYP3A4 inhibitor :	No
Log Kp (skin permeation) :	-4.0 cm/s

Lipophilicity

Log Po/w (iLOGP) :	3.78
Log Po/w (XLOGP3) :	7.15
Log Po/w (WLOGP) :	7.75
Log Po/w (MLOGP) :	5.63
Log Po/w (SILICOS-IT) :	7.33
Consensus Log Po/w :	6.33

Druglikeness

Lipinski :	1.0
Ghose :	None
Veber :	0.0
Egan :	1.0
Muegge :	1.0
Bioavailability Score :	0.56

Water Solubility

Log S (ESOL) :	-6.83
Solubility :	0.0000667 mg/ml ; 0.000000147 mol/l
Class :	Poorly soluble
Log S (Ali) :	-8.11
Solubility :	0.00000351 mg/ml ; 0.0000000077 mol/l
Class :	Poorly soluble
Log S (SILICOS-IT) :	-6.85
Solubility :	0.0000642 mg/ml ; 0.000000141 mol/l
Class :	Poorly soluble

Medicinal Chemistry

PAINS :	0.0 alert
Brenk :	1.0 alert
Leadlikeness :	2.0
Synthetic accessibility :	5.77

Safety of [ 28282-25-9 ]

Signal Word:	Warning	Class:	N/A
Precautionary Statements:	P261-P305+P351+P338	UN#:	N/A
Hazard Statements:	H302-H315-H319-H335	Packing Group:	N/A
GHS Pictogram:

Application In Synthesis of [ 28282-25-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

Downstream synthetic route of [ 28282-25-9 ]

[ 28282-25-9 ] Synthesis Path-Downstream 1~43

1
[ 908094-01-9 ]
[ 28282-25-9 ]
[ 28282-56-6 ]

Yield	Reaction Conditions	Operation in experiment
	With diethyl ether β-elemonic acid methyl ester substance of unknown configurative homogeneity;

Reference： [1]Ruzicka; Rey; Spillmann [Helvetica Chimica Acta, 1942, vol. 25, p. 1375,1390] Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447] Ruzicka et al. [Helvetica Chimica Acta, 1932, vol. 15, p. 681,690]

2
[ 28282-25-9 ]
[ 28368-21-0 ]

Yield	Reaction Conditions	Operation in experiment
	With ethanol; hydrazine hydrate anschliessendes Erhitzen mit Natriumamylat in Amylalkohol auf 180grad;

Reference： [1]Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447]

3
[ 28282-25-9 ]
25-bromo-3-oxo-tirucallen-⁽⁸⁾-oic acid-⁽²¹⁾ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With chloroform; hydrogen bromide

Reference： [1]Mladenovic; Berkes [Monatshefte fur Chemie, 1939, vol. 72, p. 417,421][Monatshefte fuer Chemie, 1936, vol. 67, p. 36,39]

4
[ 28282-25-9 ]
3-hydroxyimino-tirucalla-8,24-dien-21-oic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	β-elemonic acid-oxime substance of unknown configurative homogeneity;

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1943, vol. 26, p. 1659,1664]

5
[ 28282-25-9 ]
24ξ,25-dibromo-3-oxo-tirucallen-(8)-oic acid-(21) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With chloroform; bromine

Reference： [1]Mladenovic; Berkes [Monatshefte fur Chemie, 1939, vol. 72, p. 417,421][Monatshefte fuer Chemie, 1936, vol. 67, p. 36,39]

6
[ 28282-25-9 ]
3,3'-azino-di-tirucalla-8,24-dien-21-oic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With girard's reagent T; acetic acid β-elemonic acid azinesubstance of unknown configurative homogeneity;

Reference： [1]Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447]

7
[ 28282-25-9 ]
tirucallen-⁽⁸⁾-oic acid-⁽²¹⁾ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With hydrogenchloride; amalgamated zinc; acetic acid
	Multi-step reaction with 2 steps 1: platinum; acetic acid / Hydrogenation 2: hydrazine hydrate; ethanolic sodium ethylate / 200 °C

Reference： [1]Bilham; Kon [Journal of the Chemical Society, 1942, p. 544,545][Journal of the Chemical Society, 1943, p. 704]
[2]Bilham; Kon [Journal of the Chemical Society, 1942, p. 544,545][Journal of the Chemical Society, 1943, p. 704]

8
[ 28282-25-9 ]
[ 115788-11-9 ]

Yield	Reaction Conditions	Operation in experiment
	With ethanol; acetic acid; platinum Hydrogenation;

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1943, vol. 26, p. 1659,1664] Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447]

9
[ 28282-25-9 ]
[ 3564-57-6 ]

Yield	Reaction Conditions	Operation in experiment
	With palladium on activated charcoal; acetic acid Hydrogenation;
	With ethyl acetate; platinum Hydrogenation;
	With ethanol; platinum Hydrogenation;

With acetic acid; platinum Hydrogenation;

Reference： [1]Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447] Mladenovic; Berkes [Monatshefte fur Chemie, 1936, vol. 67, p. 36,40][Monatshefte fuer Chemie, 1939, vol. 72, p. 417,418]
[2]Ruzicka et al. [Helvetica Chimica Acta, 1932, vol. 15, p. 1466] Mladenovic; Berkes [Monatshefte fur Chemie, 1939, vol. 72, p. 417,421][Monatshefte fuer Chemie, 1936, vol. 67, p. 36,39]
[3]Ruzicka et al. [Helvetica Chimica Acta, 1932, vol. 15, p. 1466] Mladenovic; Berkes [Monatshefte fur Chemie, 1939, vol. 72, p. 417,421][Monatshefte fuer Chemie, 1936, vol. 67, p. 36,39]
[4]Bilham; Kon [Journal of the Chemical Society, 1942, p. 544,545][Journal of the Chemical Society, 1943, p. 704]

Yield	Reaction Conditions	Operation in experiment
	entspr. Ester (V), KOH;

14
[ 82509-40-8 ]
[ 28282-25-9 ]

Yield	Reaction Conditions	Operation in experiment
	at 270 - 300℃;

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1943, vol. 26, p. 1659,1664]

15
[ 28282-25-9 ]
21.24-cyclo-20ξH-tirucalladiene-(8.24)-dione-(3.21) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With phosphorus pentoxide; benzene stereoisomer(ic) of mp: 183 degree;

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1947, vol. 30, p. 2119,2122]

16
[ 28282-25-9 ]
21.24-cyclo-20ξH-tirucalladiene-(8.24)-dione-(3.21) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	With phosphorus pentoxide; benzene stereoisomer(ic) of mp: 168 degree;

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1947, vol. 30, p. 2119,2122]

Yield	Reaction Conditions	Operation in experiment
	at 20℃;

Yield	Reaction Conditions	Operation in experiment
	Siedetemperatur;

Yield	Reaction Conditions	Operation in experiment
	Hydrogenation;

Yield	Reaction Conditions	Operation in experiment
	Hydrogenation;

Yield	Reaction Conditions	Operation in experiment
	Hydrogenation;

Yield	Reaction Conditions	Operation in experiment
	Hydrogenation;

Yield	Reaction Conditions	Operation in experiment
	Hydrogenation;

Yield	Reaction Conditions	Operation in experiment
	at 125℃; Hydrogenation;

27
[ 28282-25-9 ]
13α.14β.17βH.20β_FH-lanostadiene-(8.24)-diol-(3ξ.21) [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: diethyl ether 2: amyl alcohol; sodium

Reference： [1]Ruzicka; Haeusermann [Helvetica Chimica Acta, 1942, vol. 25, p. 439,447]

28
[ 28282-25-9 ]
tirucallen-⁽⁸⁾-oic acid-⁽²¹⁾-methyl ester [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: amalgamated zinc; aqueous hydrochloric acid; acetic acid 2: diethyl ether
	Multi-step reaction with 3 steps 1: platinum; acetic acid / Hydrogenation 2: hydrazine hydrate; ethanolic sodium ethylate / 200 °C 3: diethyl ether

29
[ 28282-25-9 ]
methyl 3-oxotirucall-8-en-21-oate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: platinum; ethanol / Hydrogenation 2: diethyl ether

Reference： [1]Ruzicka et al. [Helvetica Chimica Acta, 1932, vol. 15, p. 1466]

30
[ 28282-25-9 ]
N-((E)-2-(3-oxo-tirucall-1,8,24-trien-21-((benzyloxy)carbonyl)-2(1H)-ethylidene)-carbonyl)-piperazine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: sodium hydroxide / water; ethanol / 8 h / 90 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

Reference： [1]Li, Xiaojing; Li, Lei; Zhou, Qingtong; Zhang, Na; Zhang, Shuzhi; Zhao, Rui; Liu, Dan; Jing, Yongkui; Zhao, Linxiang [Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 24, p. 5612 - 5615]

31
[ 28282-25-9 ]
N-((E)-2-(3-oxo-tirucall-1,8,24-trien-21-((benzyloxy)carbonyl)-2(1H)-ethylidene)-carbonyl)-N-methyl piperazine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: sodium hydroxide / water; ethanol / 8 h / 90 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

32
[ 28282-25-9 ]
3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-amine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: ammonia / dichloromethane; tetrahydrofuran / 0.5 h / 20 °C

33
[ 28282-25-9 ]
3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-nitrile [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 5 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: ammonia / dichloromethane; tetrahydrofuran / 0.5 h / 20 °C 5: triethylamine; trifluoroacetic anhydride / tetrahydrofuran / 2 h / 0 - 20 °C

34
[ 28282-25-9 ]
3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-tetrazole [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 6 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: ammonia / dichloromethane; tetrahydrofuran / 0.5 h / 20 °C 5: triethylamine; trifluoroacetic anhydride / tetrahydrofuran / 2 h / 0 - 20 °C 6: sodium azide; triethylamine hydrochloride / 1-methyl-pyrrolidin-2-one / 3 h / 150 °C

35
[ 28282-25-9 ]
C₃₄H₄₅ClO₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h

36
[ 28282-25-9 ]
C₃₉H₅₁ClO₄ [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 3 steps 1: potassium carbonate / 3 h / 100 °C 2: sodium hydroxide / water; ethanol / 8 h / 90 °C 3: oxalyl dichloride / dichloromethane / 0.5 h

37
[ 28282-25-9 ]
3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carboxylic acid [ No CAS ]
3,7-dioxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carboxylic acid [ No CAS ]
3,11-dioxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carboxylic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C

38
[ 28282-25-9 ]
N-(3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carbonyl)-piperazine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

39
[ 28282-25-9 ]
N-(3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carbonyl)-N-methyl piperazine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

40
[ 28282-25-9 ]
N,N-(3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-carbonyl)-dimethylamine [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

41
[ 28282-25-9 ]
methyl 3-oxo-25,26,27-trinortirucall-8,24-dien-21-((benzyloxy)carbonyl)-24-oate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 4 steps 1: potassium carbonate / 3 h / 100 °C 2: potassium carbonate; potassium permanganate; sodium periodate / water; <i>tert</i>-butyl alcohol / 24 h / 30 - 60 °C 3: oxalyl dichloride / dichloromethane / 0.5 h 4: 0.17 h / 20 °C

42
[ 28282-25-9 ]
(E)-2-(3-oxo-tirucall-1,8,24-trien-21-((benzyloxy)carbonyl)-2(1H)-ethylidene)-carboxylic acid [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
	Multi-step reaction with 2 steps 1: potassium carbonate / 3 h / 100 °C 2: sodium hydroxide / water; ethanol / 8 h / 90 °C

43
[ 28282-25-9 ]
[ 100-39-0 ]
benzyl 3-oxo-tirucall-8,24-dien-21-oate [ No CAS ]

Yield	Reaction Conditions	Operation in experiment
96.1%	With potassium carbonate at 100℃; for 3h;	1.1. Benzyl 3-oxo-tirucall-8,24-dien-21-oate (2) A mixture of 1 (1.8 g, 3.9 mmol), BrBn (0.5 mL, 4.2 mmol) and K2CO3 (1.1g, 8.0 mmol) were stirred at 100 °C for 3 h, cooled to room temperature and then poured into water (100 mL). The precipitate was filtered, washed with water to pH 7 and dried Then the product was purified by column chromatography on silica gel with cyclohexane : acetone (v:v) = 200:1, affording the desired product 2. Yield 96.1%, M.p.: 75.6-77.0 °C. IR (KBr): 3433.2, 2958.9, 2870.7, 1726.3, 1703.0, 1455.1, 1377.0, 1138.9, 755.4, 701.7 cm-1. 1H NMR (CDCl3): δ 7.37 (5H, m, -CH2Ph),5.14 (1H, d, J=12.3 Hz, -CH2Ph), 5.06 (1H, d, J=12.3 Hz, -CH2Ph), 5.06 (1H, m,H24), 2.55 (1H, m, H2), 2.46 (1H, m, H2), 2.33 (1H, m, H20), 1.66 (3H, s), 1.51 (3H,s), 1.09 (3H, s), 1.05 (3H, s), 1.03 (3H, s), 0.87 (3H, s), 0.77 (3H, s). LC-MS: 545.3(M+H)+, 567.3 (M+Na)+.

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Code	Phrase
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P370 + P378	In case of fire:
P370 + P380	In case of fire: Evacuate area.
P370 + P380 + P375	In case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P371 + P380 + P375	In case of major fire and large quantities: Evacuate area. Fight fire remotely due to the risk of explosion.
Storage
Code	Phrase
P401
P402	Store in a dry place.
P403	Store in a well-ventilated place.
P404	Store in a closed container.
P405	Store locked up.
P406	Store in corrosive resistant/ container with a resistant inner liner.
P407	Maintain air gap between stacks/pallets.
P410	Protect from sunlight.
P411
P412	Do not expose to temperatures exceeding 50 oC/ 122 oF.
P413
P420	Store away from other materials.
P422
P402 + P404	Store in a dry place. Store in a closed container.
P403 + P233	Store in a well-ventilated place. Keep container tightly closed.
P403 + P235	Store in a well-ventilated place. Keep cool.
P410 + P403	Protect from sunlight. Store in a well-ventilated place.
P410 + P412	Protect from sunlight. Do not expose to temperatures exceeding 50 oC/122oF.
P411 + P235	Keep cool.
Disposal
Code	Phrase
P501	Dispose of contents/container to ...
P502	Refer to manufacturer/supplier for information on recovery/recycling

Physical hazards
Code	Phrase
H200	Unstable explosive
H201	Explosive; mass explosion hazard
H202	Explosive; severe projection hazard
H203	Explosive; fire, blast or projection hazard
H204	Fire or projection hazard
H205	May mass explode in fire
H220	Extremely flammable gas
H221	Flammable gas
H222	Extremely flammable aerosol
H223	Flammable aerosol
H224	Extremely flammable liquid and vapour
H225	Highly flammable liquid and vapour
H226	Flammable liquid and vapour
H227	Combustible liquid
H228	Flammable solid
H229	Pressurized container: may burst if heated
H230	May react explosively even in the absence of air
H231	May react explosively even in the absence of air at elevated pressure and/or temperature
H240	Heating may cause an explosion
H241	Heating may cause a fire or explosion
H242	Heating may cause a fire
H250	Catches fire spontaneously if exposed to air
H251	Self-heating; may catch fire
H252	Self-heating in large quantities; may catch fire
H260	In contact with water releases flammable gases which may ignite spontaneously
H261	In contact with water releases flammable gas
H270	May cause or intensify fire; oxidizer
H271	May cause fire or explosion; strong oxidizer
H272	May intensify fire; oxidizer
H280	Contains gas under pressure; may explode if heated
H281	Contains refrigerated gas; may cause cryogenic burns or injury
H290	May be corrosive to metals
Health hazards
Code	Phrase
H300	Fatal if swallowed
H301	Toxic if swallowed
H302	Harmful if swallowed
H303	May be harmful if swallowed
H304	May be fatal if swallowed and enters airways
H305	May be harmful if swallowed and enters airways
H310	Fatal in contact with skin
H311	Toxic in contact with skin
H312	Harmful in contact with skin
H313	May be harmful in contact with skin
H314	Causes severe skin burns and eye damage
H315	Causes skin irritation
H316	Causes mild skin irritation
H317	May cause an allergic skin reaction
H318	Causes serious eye damage
H319	Causes serious eye irritation
H320	Causes eye irritation
H330	Fatal if inhaled
H331	Toxic if inhaled
H332	Harmful if inhaled
H333	May be harmful if inhaled
H334	May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335	May cause respiratory irritation
H336	May cause drowsiness or dizziness
H340	May cause genetic defects
H341	Suspected of causing genetic defects
H350	May cause cancer
H351	Suspected of causing cancer
H360	May damage fertility or the unborn child
H361	Suspected of damaging fertility or the unborn child
H361d	Suspected of damaging the unborn child
H362	May cause harm to breast-fed children
H370	Causes damage to organs
H371	May cause damage to organs
H372	Causes damage to organs through prolonged or repeated exposure
H373	May cause damage to organs through prolonged or repeated exposure
Environmental hazards
Code	Phrase
H400	Very toxic to aquatic life
H401	Toxic to aquatic life
H402	Harmful to aquatic life
H410	Very toxic to aquatic life with long-lasting effects
H411	Toxic to aquatic life with long-lasting effects
H412	Harmful to aquatic life with long-lasting effects
H413	May cause long-lasting harmful effects to aquatic life
H420	Harms public health and the environment by destroying ozone in the upper atmosphere

[ CAS No. 28282-25-9 ] {[proInfo.proName]}

Quality Control of [ 28282-25-9 ]

Related Doc. of [ 28282-25-9 ]

Product Details of [ 28282-25-9 ]

Calculated chemistry of [ 28282-25-9 ]

Physicochemical Properties

Pharmacokinetics

Lipophilicity

Druglikeness

Water Solubility

Medicinal Chemistry

Safety of [ 28282-25-9 ]

Application In Synthesis of [ 28282-25-9 ]

[ 28282-25-9 ] Synthesis Path-Downstream 1~43

Precautionary Statements-General

Prevention

Response

Storage

Disposal

Physical hazards

Health hazards

Environmental hazards

Inquiry