Home Cart 0 Sign in  

[ CAS No. 28918-16-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 28918-16-3
Chemical Structure| 28918-16-3
Structure of 28918-16-3 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 28918-16-3 ]

Related Doc. of [ 28918-16-3 ]

Alternatived Products of [ 28918-16-3 ]

Product Details of [ 28918-16-3 ]

CAS No. :28918-16-3 MDL No. :
Formula : C12H12N2O Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 200.24 Pubchem ID :-
Synonyms :

Safety of [ 28918-16-3 ]

Signal Word: Class:
Precautionary Statements: UN#:
Hazard Statements: Packing Group:

Application In Synthesis of [ 28918-16-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 28918-16-3 ]

[ 28918-16-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 288-32-4 ]
  • [ 936-59-4 ]
  • [ 28918-16-3 ]
YieldReaction ConditionsOperation in experiment
83% With triethylamine; In toluene; at 20℃;Reflux; General Procedure:To a solution of 3-chloro-1-phenylpropan-1-one (2, 2.0 mmol) in toluene (25-30 mL) was added azoles (3.0 mmol) and triethylamine (4.0 mmol) at room temperature. The reaction mixture was heated at reflux under stirring for 3-4h in an oil bath. Solvent was distilled off under reduced pressure and the residue was taken into ethyl acetate (20 mL). Organic layer was washed with water (10 mL x 3) and dried over sodium sulfate. Sodium sulfate was filtered off and washed with ethyl acetate (5 mL x 2). The combined filtrate was concentrated under reduced pressure to yield crude product which was purified by recrystallization with ethyl acetate/hexane to give 3-(substituted 1H- azol-1-yl)-1-phenylpropan-1-one (3-9).
Same Skeleton Products
Historical Records