Alternatived Products of [ 3319-01-5 ]
Product Details of [ 3319-01-5 ]
CAS No. : | 3319-01-5 |
MDL No. : | MFCD00014642 |
Formula : |
C11H21N
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
167.29
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 3319-01-5 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Upstream synthesis route of [ 3319-01-5 ]
- Downstream synthetic route of [ 3319-01-5 ]
- 1
-
[ 110-89-4 ]
-
[ 56528-77-9 ]
-
[ 3319-01-5 ]
-
[ 531-67-9 ]
-
[ 92-51-3 ]
- 2
-
[ 110-89-4 ]
-
[ 110-82-7 ]
-
[ 56528-77-9 ]
-
[ 3319-01-5 ]
-
[ 531-67-9 ]
-
[ 92-51-3 ]
- 3
-
[ 110-82-7 ]
-
[ 56528-77-9 ]
-
[ 3319-01-5 ]
-
[ 531-67-9 ]
-
[ 92-51-3 ]
- 4
-
[ 110-89-4 ]
-
[ 101-84-8 ]
-
[ 3319-01-5 ]
-
[ 4096-20-2 ]
Yield | Reaction Conditions | Operation in experiment |
1: 28%
2: 56% |
With sodium tetrahydroborate; 10 wt% Pd(OH)2 on carbon; water In toluene at 150℃; for 24h; Inert atmosphere; Sealed tube; |
|
1: 56%
2: 28% |
With sodium tetrahydroborate; 10 wt% Pd(OH)2 on carbon In water at 160℃; for 24h; Inert atmosphere; |
1 Example 1
A moderate stirrer was placed in a dry reaction tube (20 ml), palladium hydroxide/carbon (30 mol%), NaBH4 (1.5 equivalents) was added, and then the reaction tube was evacuated, filled with argon gas, and repeatedly replaced three times. A solution of diphenyl ether (0.2 mmol) and hexahydropyridine (0.7 mmol) dissolved in a solvent was slowly added to the reaction tube with a syringe under an argon atmosphere, and 10 uL of water was added to the reaction tube using a micro-injector, followed by a syringe. 1 mL of air was added to the reaction tube, and the reaction tube was placed in an oil bath at 160 ° C to heat and stir the reaction. After 24 hours, the reaction was stopped, the reaction tube was taken out from the oil bath, cooled to room temperature, diluted with ethyl acetate, and then filtered over Celite, and the yield of benzene in the gas phase was 85%. The filtrate was concentrated and separated using an activated thin layer chromatography plate (eluent: n-hexane / ethyl acetate = 100/1) to give the final products 3a and 4a. Product 3a (yield: 56%) |
Reference:
[1]Zeng, Huiying; Cao, Dawei; Qiu, Zihang; Li, Chao-Jun
[Angewandte Chemie - International Edition, 2018, vol. 57, # 14, p. 3752 - 3757][Angew. Chem., 2018, vol. 130, p. 3814 - 3819,6]
[2]Current Patent Assignee: LANZHOU UNIVERSITY - CN109553592, 2019, A
Location in patent: Paragraph 0024-0026