Alternatived Products of [ 36313-98-1 ]
Product Details of [ 36313-98-1 ]
CAS No. : | 36313-98-1 |
MDL No. : | MFCD11107428 |
Formula : |
C5H3ClN2O4
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
190.54
|
Pubchem ID : | - |
Synonyms : |
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Safety of [ 36313-98-1 ]
Signal Word: | |
Class: | N/A |
Precautionary Statements: | |
UN#: | N/A |
Hazard Statements: | |
Packing Group: | N/A |
Application In Synthesis of [ 36313-98-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 36313-98-1 ]
- 1
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[ 65-86-1 ]
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[ 36313-98-1 ]
Yield | Reaction Conditions | Operation in experiment |
92% |
|
78 g (0.50 mol) of <strong>[65-86-1]orotic acid</strong> (B0) is added to 700 ml of acetic acid and 25 ml of acetic anhydride and a catalytic amount of ferric chloride are added, plusHeat to 90-95C and add 108g (0.80mol) of sulfonyl chloride (FW135) dropwise. After the addition is complete, heat to reflux overnight until the methyl orotate is completely chlorinated (TLC detection) to stop the reaction. Cool the reaction solution to 10C.The solid was collected by filtration, washed sequentially with acetic acid and water, and dried with hot air to give a yellow solid. Melting point: mp: 288 C., yielding 88.0 g (0.46 mol) of alpha-chloro<strong>[65-86-1]orotic acid</strong> (B1), molar yield 92%. |