Alternatived Products of [ 452056-80-3 ]
Product Details of [ 452056-80-3 ]
CAS No. : | 452056-80-3 |
MDL No. : | MFCD19441204 |
Formula : |
C13H11FN2O
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Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
230.24
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 452056-80-3 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 452056-80-3 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 452056-80-3 ]
- 1
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[ 54221-95-3 ]
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[ 452056-80-3 ]
- 2
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[ 5327-32-2 ]
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[ 452056-80-3 ]
Yield | Reaction Conditions | Operation in experiment |
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Multi-step reaction with 3 steps
1.1: 42 percent / potassium permanganate / H2O / 2.5 h / 50 - 90 °C
2.1: carbonyldiimidazole / dimethylformamide / 0.75 h / 20 °C
2.2: 65 percent / potassium tert-butoxide / dimethylformamide / 2 h / 120 °C
3.1: 55 percent / HBr / H2O / 30 h / Heating |
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Multi-step reaction with 3 steps
1: potassium permanganate / water / 20 - 90 °C
2: 1,1'-carbonyldiimidazole
3: hydrogen bromide |
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Reference:
[1]Wagner, Gerd K.; Kotschenreuther, Dunja; Zimmermann, Werner; Laufer, Stefan A.
[Journal of Organic Chemistry, 2003, vol. 68, # 11, p. 4527 - 4530]
[2]Albrecht, Wolfgang; Unger, Anke; Bauer, Silke M.; Laufer, Stefan A.
[Journal of Medicinal Chemistry, 2017, vol. 60, # 13, p. 5290 - 5305]