Alternatived Products of [ 46399-02-4 ]
Product Details of [ 46399-02-4 ]
CAS No. : | 46399-02-4 |
MDL No. : | |
Formula : |
C10H16N2O3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
212.25
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Pubchem ID : | - |
Synonyms : |
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Safety of [ 46399-02-4 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 46399-02-4 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 46399-02-4 ]
- 1
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[ 54221-37-3 ]
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[ 107-15-3 ]
-
[ 46399-02-4 ]
Yield | Reaction Conditions | Operation in experiment |
86% |
With potassium carbonate In acetonitrile at 20℃; for 18h; |
XIV.A
Step A: Preparation of 16; To a solution of 1,2-ethylene diamine (2.0 mL, 29.9 mmol, 2.1 eq.) and K2CO3 (4.0 g, 28.9 mmol, 2.0 eq.) in CH3CN (30 mL) at room temperature was added a solution of diethyl meso-2,5-dibromoadipate (5.1 g, 14.2 mmol, 1.0 eq.) in CH3CN (20 mL) over 2 hours. The reaction mixture was stirred at room temperature for 16 hours. The resulting mixture was filtered, the precipitate washed with dichloromethane and the filtrate was concentrated under reduced pressure. The crude product was purified by flash chromatography on silica gel, eluting with dichloromethane-methanol (100:0 to 90:10) to afford 16 (2.6 g, 86%) as a white solid. |
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