Home Cart 0 Sign in  
X

[ CAS No. 474709-06-3 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
3d Animation Molecule Structure of 474709-06-3
Chemical Structure| 474709-06-3
Chemical Structure| 474709-06-3
Structure of 474709-06-3 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Search after Editing

* Storage: {[proInfo.prStorage]}

* Shipping: {[proInfo.prShipping]}

Quality Control of [ 474709-06-3 ]

Related Doc. of [ 474709-06-3 ]

Alternatived Products of [ 474709-06-3 ]
Product Citations

Product Details of [ 474709-06-3 ]

CAS No. :474709-06-3 MDL No. :MFCD13193294
Formula : C7H4BrFN2 Boiling Point : -
Linear Structure Formula :- InChI Key :XCCQWSWEMFBIEU-UHFFFAOYSA-N
M.W : 215.02 Pubchem ID :22031933
Synonyms :

Safety of [ 474709-06-3 ]

Signal Word:Warning Class:N/A
Precautionary Statements:P261-P305+P351+P338 UN#:N/A
Hazard Statements:H302-H315-H319-H335 Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 474709-06-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 474709-06-3 ]

[ 474709-06-3 ] Synthesis Path-Downstream   1~4

  • 2
  • [ 474709-05-2 ]
  • [ 474709-06-3 ]
YieldReaction ConditionsOperation in experiment
249 Production Example 249 6-Bromo-8-fluoxoimidazo[1,2-a]pyridine 46 mg of the title compound (pale yellow crystals) was obtained from 87 mg of 6-bromo-8-fluoro-2,3-dihydroimidazo[1,2-a]pyridine in the same manner as in Production Example 234.1H-NMR (CDCl3) δ: 7.03(dd, J=9.6, 1.6Hz, 1H), 7.63(d, J=3.6Hz, 1H), 7.67(s, 1H), 8.12-8.15(m, 1H)
  • 3
  • [ 474709-06-3 ]
  • [ 73183-34-3 ]
  • {8-fluoroimidazo[1,2-a]pyridin-6-yl}boronic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
100% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate In N,N-dimethyl-formamide at 80℃; for 3h; Inert atmosphere; 120.A Procedure A2: Preparation of 5-(tetramethyl- 1, 3,2-dioxaborolan-2-yI)- IH-indazole General procedure: In a pressure tube, 5-bromo-1 H-indazole (400 mg, 2 mmol), bis(pinacolato)diboron (773 mg, 3 mmol) and KOAc (598 mg, 6 mmol) were dissolved in 40 mL of dry DMF and sparged with argon for 10 mi Pd(dppf)012 (149 mg, 0.2 mmol) was added in one portion, and the reactionmixture was sparged with argon for additional 3 mm. The pressure tube was capped and the reaction mixture was heated at 10000 overnight. After full conversion (monitored by LOMS), the reaction mixture was filtered throught Celite and the filtrate was concentrated under reduced pressure. The residue was dissolved in EtOAc and co-evaporated with silica. Product was purified by column chromatography, eluting with hexane:EtOAc (0-50%) to afford the title product asa white solid (0.5 g, 2 mmol, quant.). ESI-MS: 245.1 [M+H]+. 1 H NMR (300 MHz, DMSO-d6) 613.15 (s, 1H), 8.16 (s, 1H), 8.12 (s, 1H), 7.61 (dd, J = 8.4, 1.1 Hz, 1H), 7.52 (dt, J = 8.4, 1.0 Hz,1H), 1.31 (s, 12H).
  • 4
  • [ 474709-06-3 ]
  • 5-{8-fluoroimidazo[1,2-a]pyridin-6-yl}-6-(3-fluorophenyl)imidazo[1,2-a]pyrazin-8-amine hydrochloride [ No CAS ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / N,N-dimethyl-formamide / 3 h / 80 °C / Inert atmosphere 2: bis(di-tert-​butyl(4-​dimethylaminophenyl)​phosphine)​dichloropalladium(II); potassium carbonate / 1,4-dioxane; water / 2 h / 120 °C
Recommend Products
Same Skeleton Products
Historical Records

Related Functional Groups of
[ 474709-06-3 ]

Fluorinated Building Blocks

Chemical Structure| 1368664-08-7

[ 1368664-08-7 ]

8-Bromo-6-fluoroimidazo[1,2-a]pyridine

Similarity: 0.98

Chemical Structure| 1260817-61-5

[ 1260817-61-5 ]

3,6-Dibromo-8-fluoroimidazo[1,2-a]pyridine

Similarity: 0.86

Chemical Structure| 1446334-75-3

[ 1446334-75-3 ]

6-Bromo-8-fluoro-2-methylimidazo[1,2-a]pyridine

Similarity: 0.85

Bromides

Chemical Structure| 1368664-08-7

[ 1368664-08-7 ]

8-Bromo-6-fluoroimidazo[1,2-a]pyridine

Similarity: 0.98

Chemical Structure| 1260817-61-5

[ 1260817-61-5 ]

3,6-Dibromo-8-fluoroimidazo[1,2-a]pyridine

Similarity: 0.86

Chemical Structure| 1446334-75-3

[ 1446334-75-3 ]

6-Bromo-8-fluoro-2-methylimidazo[1,2-a]pyridine

Similarity: 0.85

Related Parent Nucleus of
[ 474709-06-3 ]

Other Aromatic Heterocycles

Chemical Structure| 1368664-08-7

[ 1368664-08-7 ]

8-Bromo-6-fluoroimidazo[1,2-a]pyridine

Similarity: 0.98

Chemical Structure| 1260817-61-5

[ 1260817-61-5 ]

3,6-Dibromo-8-fluoroimidazo[1,2-a]pyridine

Similarity: 0.86

Chemical Structure| 1446334-75-3

[ 1446334-75-3 ]

6-Bromo-8-fluoro-2-methylimidazo[1,2-a]pyridine

Similarity: 0.85