Alternatived Products of [ 55218-08-1 ]
Product Details of [ 55218-08-1 ]
CAS No. : | 55218-08-1 |
MDL No. : | MFCD13689018 |
Formula : |
C13H12O3
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
216.23
|
Pubchem ID : | - |
Synonyms : |
|
Safety of [ 55218-08-1 ]
Signal Word: | |
Class: | |
Precautionary Statements: | |
UN#: | |
Hazard Statements: | |
Packing Group: | |
Application In Synthesis of [ 55218-08-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 55218-08-1 ]
- 1
-
[ 5486-55-5 ]
-
[ 68-12-2 ]
-
[ 55218-08-1 ]
-
[ 58671-26-4 ]
- 2
-
[ 141-82-2 ]
-
[ 5486-55-5 ]
-
[ 55218-08-1 ]
- 3
-
[ 5486-55-5 ]
-
[ 93-61-8 ]
-
[ 55218-08-1 ]
- 4
-
[ 4885-02-3 ]
-
[ 5486-55-5 ]
-
[ 55218-08-1 ]
Yield | Reaction Conditions | Operation in experiment |
|
titanium tetrachloride; In dichloromethane; |
PREPARATION 21 2,6-Dimethoxy-1-naphthaldehyde By the method of Preparation 1, <strong>[5486-55-5]2,6-dimethoxynaphthalene</strong> (5 g., 26 mmoles) in 150 ml. of methylene chloride was reacted with titanium tetrachloride (19.7 g., 11.4 ml., 104 mmoles) and 1,1-dichloromethyl methyl ether (8.9 g., 78 mmoles). The resulting crude product was recrystallized from toluene, affording purified 2,6-dimethoxy-1-naphthaldehyde (1.0 g., m.p. 285°-288° C.). |
- 5
-
[ 5486-55-5 ]
-
[ 68-12-2 ]
-
[ 55218-08-1 ]
- 6
-
[ 1535-67-7 ]
-
[ 5486-55-5 ]
-
[ 55218-08-1 ]
Yield | Reaction Conditions | Operation in experiment |
93% |
|
General procedure: In a round-bottomed flask equipped with a stirring bar and rubber septum was placed a 1 M solution of SnCl4 in anhydrous CH2Cl2 (1 mL, 1 mmol). To this solution was added PhSCF2H (1; 240.2 mg, 1.5 mmol) in anhydrous CH2Cl2 (1.5 mL), followed by a solution of an aromatic compound (0.5 mmol) in anhydrous CH2Cl2 (1 mL). The reaction was allowed to proceed for 2 h before it was quenched with a solution of IBX (140 mg, 0.5 mmol) in DMSO/H2O (4 mL; 3:1 v:v). After 2 h of stirring at rt, the reaction mixture was quenched by addition of a saturated aqueous solution of sodium thiosulfate (10 mL), then basified with a saturated aqueous solution of sodium hydrogen carbonate (10 mL), followed by stirring and extraction with CH2Cl2 (3 × 10 mL). The combined organic layers were washed with water (3 × 10 mL) and brine (10 mL), dried (anhydrous MgSO4), filtered and concentrated (aspirator). The residue was purified by PTLC, radial chromatography or column chromatography to furnish analytically pure product. |