Alternatived Products of [ 60789-55-1 ]
Product Details of [ 60789-55-1 ]
CAS No. : | 60789-55-1 |
MDL No. : | MFCD09032384 |
Formula : |
C13H16O
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
188.27
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 60789-55-1 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 60789-55-1 ]
- 1
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[ 60789-54-0 ]
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[ 1066-26-8 ]
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[ 60789-55-1 ]
- 2
-
[ 72517-23-8 ]
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[ 60789-55-1 ]
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5-(6-benzyloxyhexynyl)-2,3-dimethoxybenzoic acid
[ No CAS ]
Yield | Reaction Conditions | Operation in experiment |
62.3% |
|
Dissolve 0.6 g (2.3 mmol) of <strong>[72517-23-8]5-bromo-2,3-dimethoxybenzoic acid</strong> in 15 ml of diethylamine, add 8.4 mg of Pd (PPh3) 2Cl2 and 4.4 mg of CuI,After argon gas was purged at 80 C for 30 minutes, a solution of 0.649 g of O-benzyl-5-hexyn-1-ol in Preparation 3 in 2 ml of diethylamine was added dropwise and the mixture was stirred at room temperature for 5 hours and refluxed overnight. The reaction was evaporated to drynessliquid,To the resulting brown residue was added 80 mL of EtOAc, 80 mL of washed with saturated brine and three times of washing. The organic layer was dried over Na2SO4, filtered and evaporated to dryness to give a reddish brown oil.300-400 mesh silica gel preparative separation, the mobile phase of petroleum ether: ethyl acetate = 4: 1, the target component was collected yellow oil 0.527g, yield 62.3% |