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[ CAS No. 66937-93-7 ] {[proInfo.proName]}

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Chemical Structure| 66937-93-7
Chemical Structure| 66937-93-7
Structure of 66937-93-7 * Storage: {[proInfo.prStorage]}
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Product Details of [ 66937-93-7 ]

CAS No. :66937-93-7 MDL No. :
Formula : C9H17NO2 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 171.24 Pubchem ID :-
Synonyms :

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Application In Synthesis of [ 66937-93-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 66937-93-7 ]

[ 66937-93-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 4021-08-3 ]
  • [ 71-41-0 ]
  • [ 66937-93-7 ]
  • 2
  • [ 123387-50-8 ]
  • [ 66937-93-7 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 2 steps 1: 60 percent Turnov. / sec-BuLi; TMEDA / diethyl ether / 5 h / -90 - 20 °C 2: 100 percent / HCl / ethyl acetate
  • 3
  • [ 66937-93-7 ]
  • [ 2743-38-6 ]
  • ethyl (2R,4S)-4-methyl-2-piperidinecarboxylate L-(-)-dibenzoyl tartrate [ No CAS ]
YieldReaction ConditionsOperation in experiment
46.3% With 1-butylpyridinium bromide; In isopropyl alcohol; acetonitrile; at 65℃; 8.55 g of ethyl 4-methyl-2-piperidinecarboxylate racemate and 17.9 g of L-(-)-dibenzoyltartaric acid were addedStir in 125 mL of isopropanol and 50 mL of acetonitrile. Add 2.16g1-butyl bromide pyridine, heating at 65 C,After the reaction is completed, cool to room temperature.0.437 g of L-(-)-dibenzoyltartaric acid pyridinium salt was added, and the mixture was allowed to stand for 12 hours, and filtered.12.25 g of white crystals were obtained in a yield of 46.3%.
  • 4
  • [ 66937-93-7 ]
  • [ 147-71-7 ]
  • (2S,4S)-4-methyl-2-piperidine carboxylic acid ethyl ester D-tartaric acid salt [ No CAS ]
YieldReaction ConditionsOperation in experiment
47.6% With 1-butylpyridinium bromide In isopropyl alcohol; acetonitrile at 65℃; 1; 2 A method for separating argatroban isomer impurities, the method comprising the steps of: S1: Preparation of ethyl (2S,4S)-4-methyl-2-piperidinecarboxylate-D-tartrate (Compound I) crafting process: 8.55 g of ethyl 4-methyl-2-piperidinecarboxylate racemate and 7.5 g of D-tartaric acid, 150 mL of isopropanol and 100 mL of acetonitrile were added and stirred. 2.16 g of 1-butylbromide pyridine was added thereto, and the reaction was heated at 65 °C. After completion of the reaction, the mixture was cooled to room temperature. 0.229g pyridine was added D-tartrate salt, crystallization was allowed to stand 12h, Filtration gave 7.64 g of white crystals in a yield of 47.6%.
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