Home Cart 0 Sign in  

[ CAS No. 800401-88-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 800401-88-1
Chemical Structure| 800401-88-1
Structure of 800401-88-1 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 800401-88-1 ]

Related Doc. of [ 800401-88-1 ]

Alternatived Products of [ 800401-88-1 ]

Product Details of [ 800401-88-1 ]

CAS No. :800401-88-1 MDL No. :
Formula : C9H5N3O2 Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 187.16 Pubchem ID :-
Synonyms :

Safety of [ 800401-88-1 ]

Signal Word: Class:
Precautionary Statements: UN#:
Hazard Statements: Packing Group:

Application In Synthesis of [ 800401-88-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 800401-88-1 ]

[ 800401-88-1 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 800401-88-1 ]
  • [ 1534-90-3 ]
  • 2-[(5-cyano-1H-pyrrolo[2,3-c]pyridine-2-carbony)amino]-3-(S)-(4-fluorophenyl)propionic acid ethyl ester [ No CAS ]
YieldReaction ConditionsOperation in experiment
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 20℃; for 16.0h; To a solution OF 2-AMINO-3- (S)- (4-FLUOROPHENYL) propionic acid ethyl ester hydrochloride (0.530g, 2. 14MMOL) in DMF (15mL) was added DIPEA (1. 3mL, 7. 49MMOL), HOBt (0.290g, 2. 14MMOL), 5-cyano-lH-pyrrolo [2,3-c] pyridine-2- carboxylic acid (Preparation 62,0. 400g, 2. 14MMOL) and EDCI (0.492g, 2.57mmol). The reaction mixture was stirred at rt for 16H. Reaction mixture was concentrated in vacuo and the residue was partitioned between water (150ML) and ethyl acetate (200mL). Organic phase was separated and the aqueous phase was further extracted with ethyl acetate (200mL). The combined organic extracts were washed with saturated NAHC03 (75mL), saturated sodium chloride (LOOML), dried (MGS04), filtered and concentrated in vacuo to give the title compound. m/z (ES+) = 381 [M+ H] + ; RT = 4. 79MIN.
  • 2
  • [ 800401-70-1 ]
  • [ 800401-88-1 ]
  • 3
  • [ 21901-41-7 ]
  • [ 800401-88-1 ]
  • 4
  • [ 23056-47-5 ]
  • [ 800401-88-1 ]
Same Skeleton Products
Historical Records