Home Cart 0 Sign in  

[ CAS No. 82070-04-0 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
Chemical Structure| 82070-04-0
Chemical Structure| 82070-04-0
Structure of 82070-04-0 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 82070-04-0 ]

Related Doc. of [ 82070-04-0 ]

Alternatived Products of [ 82070-04-0 ]

Product Details of [ 82070-04-0 ]

CAS No. :82070-04-0 MDL No. :
Formula : C6H8O2S Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 144.19 Pubchem ID :-
Synonyms :

Safety of [ 82070-04-0 ]

Signal Word: Class:
Precautionary Statements: UN#:
Hazard Statements: Packing Group:

Application In Synthesis of [ 82070-04-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 82070-04-0 ]

[ 82070-04-0 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 71050-40-3 ]
  • [ 82070-04-0 ]
YieldReaction ConditionsOperation in experiment
With lithium aluminium tetrahydride; In tetrahydrofuran; LAH (1.2 g, 31.6 mmol) was tared and diluted with dry THF (150 ML) under nitrogen. Solid neat <strong>[71050-40-3]4-methoxythiophene-3-carboxylic acid</strong> (2.5 g, 15.8 mmol) was added over 10 portions. Upon completion of gas evolution, the mixture was maintained overnight, TLC monitored (50% EtOAc-hexane), and quenched at 23 C carefully with the dropwise addition of saturated aqueous Rochelle salt (15 mL). The mixture was filtered through a pad of celite, washed with ethyl acetate and concentrated in vacuo. The crude product alcohol (2.35 g, 15.9 mmol) was dissolved in CH2CI2 (80 mL), cooled to 0 C, and DMSO (10 ML) was added followed by triethylamine (6.9 mL, 47.9 mmol). Solid sulfur trioxide pyridine complex (7.6 g, 47.9 mmol) was added, and the mixture then warmed to room temperature and maintained 4 h (TLC, 50% EtOAc-hexane). The mixture was quenched with saturated aqueous sodium bicarbonate and partitioned with chloroform. The organic phase was concentrated in vacuo to provide the pure the title compound (2.6 g) in quantitative yield.
Same Skeleton Products
Historical Records