Alternatived Products of [ 822-63-9 ]
Product Details of [ 822-63-9 ]
CAS No. : | 822-63-9 |
MDL No. : | MFCD00047072 |
Formula : |
C3H4N2O2
|
Boiling Point : |
- |
Linear Structure Formula : | - |
InChI Key : | - |
M.W : |
100.08
|
Pubchem ID : | - |
Synonyms : |
|
Application In Synthesis of [ 822-63-9 ]
* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.
- Downstream synthetic route of [ 822-63-9 ]
- 1
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[ 167408-67-5 ]
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[ 822-63-9 ]
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[ 1356475-42-7 ]
Yield | Reaction Conditions | Operation in experiment |
82% |
With acetic acid for 2h; Reflux; |
Synthesis of compound 20 A mixture of compound 1 (17g, 0.1 mol) and 5-amino-isoxazol-3-one (10g,0.1 mol) in acetic acid (AcOH) (100ml_) was stirred at reflux for 2h. The reaction mixture was poured into ice/water (200ml_). The solid formed was collected by filtration and dried under high vacuum. 19g (82%) of compound 20 were obtained.1H-NMR (CDCI3): δ= 10.30 (bs, 1 H), 7.69 (s, 1 H), 4.12 (s, 3H), 2.27-2.20 (m, 1 H), 1.29- 1 .22 (m, 2H), 1 .21 -1 .12 (m, 2H).MS: m/z= 235 [M+H]+ |
82% |
With acetic acid for 2h; Reflux; |
Synthesis of compound 11
A mixture of compound 10 (17 g, 0.1 mol) and 5-amino-isoxazol-3-one (10 g, 0.1 mol) in acetic acid (AcOH) (100 ml.) was stirred at reflux for 2h. The reaction mixture was poured into ice/water (200 ml_). The solid formed was collected by filtration and dried under high vacuum. 19 g (82%) of compound 11 were obtained. H-NMR (CDCIs): δ= 10.30 (bs, 1 H), 7.69 (s, 1 H), 4.12 (s, 3H), 2.27-2.20 (m, 1 H), 1 .29- 1 .22 (m, 2H), 1 .21 -1.12 (m, 2H); MS: m/z= 235 [M+H]+ |