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[ CAS No. 82202-32-2 ]

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Cat. No.: {[proInfo.prAm]}
2D
Chemical Structure| 82202-32-2
Chemical Structure| 82202-32-2
Structure of 82202-32-2 *Storage: {[proInfo.prStorage]}

Quality Control of [ 82202-32-2 ]

Related Doc. of [ 82202-32-2 ]

SDS
Alternatived Products of [ 82202-32-2 ]
Alternatived Products of [ 82202-32-2 ]

Product Details of [ 82202-32-2 ]

CAS No. :82202-32-2MDL No. :MFCD03695812
Formula : C7H11BrN2S Boiling Point : -
Linear Structure Formula :-InChI Key :-
M.W :235.15Pubchem ID :-
Synonyms :

Computed Properties of [ 82202-32-2 ]

TPSA : - H-Bond Acceptor Count : -
XLogP3 : - H-Bond Donor Count : -
SP3 : - Rotatable Bond Count : -

Safety of [ 82202-32-2 ]

Signal Word:WarningClass:N/A
Precautionary Statements:P301+P312+P330UN#:N/A
Hazard Statements:H302Packing Group:N/A
GHS Pictogram:

Application In Synthesis of [ 82202-32-2 ]

  • Downstream synthetic route of [ 82202-32-2 ]

[ 82202-32-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 74370-93-7 ]
  • [ 82202-32-2 ]
YieldReaction ConditionsOperation in experiment
93.7% With N-Bromosuccinimide; In tetrachloromethane; at 20℃; for 1h; N-Bromosuccinimide(1.00g, 5.6mmol) was added to a solution of 2-amino-4-[(1,1-dimethyl)ethyl]thiazole(compound of Example 185(1); 0.87g, 5.6mmol) in carbon tetrachloride(9mL), and the mixture was stirred at room temperature for 1 hour. Hexane was added to the reaction mixture. The insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by column chromatography on silica gel(n-hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as an yellowish gray powder.1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).
93.7% With N-Bromosuccinimide; In tetrachloromethane; at 20℃; for 1h; N-Bromosuccinimide(1.00g, 5.6mmol) was added to a solution of 2-amino-4-[(1,1-dimethyl)ethyl]thiazole(compound of Example 185(1); 0.87g, 5.6mmol) in carbon tetrachloride(9mL), and the mixture was stirred at room temperature for 1 hour. Hexane was added to the reaction mixture. The insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by column chromatography on silica gel(n-hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as an yellowish gray powder.1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).
93.7% With N-Bromosuccinimide; In tetrachloromethane; at 20℃; for 1h; 2-Amino-4-[(1,1-dimethyl)ethyl]thiazole(compound of Example 181(1); 0.87g, 5.6mmol) was dissolved in carbon tetrachloride(9mL). N-Bromosuccinimide(1.00g, 5.6mmol) was added, and the mixture was stirred at room temperature for 1 hour. Hexane was added to the reaction mixture. The insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by chromatography on silica gel(hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as an yellowish gray powder.1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).
93.7% With N-Bromosuccinimide; In tetrachloromethane; at 20℃; for 1h; (1) 2-Amino-5-bromo-4-[(1,1-dimethyl)ethyl]thiazole. 2-Amino-4-[(1,1-dimethyl)ethyl]thiazole(compound of Example 181(1); 0.87g, 5.6mmol) was dissolved in carbon tetrachloride(9mL). N-Bromosuccinimide(1.00g, 5.6mmol) was added, and the mixture was stirred at room temperature for 1 hour. Hexane was added to the reaction mixture. The insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by chromatography on silica gel(hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as an yellowish gray powder. 1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).
93.7% With N-Bromosuccinimide; In tetrachloromethane; at 20℃; for 1h; 2-Amino-4-[(1,1-dimethyl)ethyl]thiazole(compound of Example 181(1); 0.87g, 5.6mmol) was dissolved in carbon tetrachloride(9mL). N-Bromosuccinimide(1.00g, 5.6mmol) was added, and the mixture was stirred at room temperature for 1 hour. Hexane was added to the reaction mixture. The insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by chromatography on silica gel(hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as an yellowish gray powder.1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).

  • 2
  • [ 128-08-5 ]
  • [ 74370-93-7 ]
  • [ 82202-32-2 ]
YieldReaction ConditionsOperation in experiment
93.7% In tetrachloromethane; hexane; (1) 2-Amino-5-bromo-4-[(1,1-dimethyl)ethyl]thiazole. 2-Amino-4-[(1,1-dimethyl)ethyl]thiazole(0.87g, 5.6mmol) was dissolved in carbon tetrachloride(9mL). N-Bromosuccinimide(1.00g, 5.6mmol) was added, and the mixture was stirred at room temparature for 1 hour. Hexane was added to the reaction mixture, the insoluble matter was filtered off, and the residue obtained by evaporation of the filtrate under reduced pressure was purified by chromatography on silica gel(hexane:ethyl acetate=2:1) to give the title compound(1.23g, 93.7%) as a yellowish gray powder. 1H-NMR(CDCl3): delta 1.39(9H, s), 4.81(2H, brs).
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