Home Cart 0 Sign in  

[ CAS No. 845272-21-1 ] {[proInfo.proName]}

,{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]}
HazMat Fee +

There will be a HazMat fee per item when shipping a dangerous goods. The HazMat fee will be charged to your UPS/DHL/FedEx collect account or added to the invoice unless the package is shipped via Ground service. Ship by air in Excepted Quantity (each bottle), which is up to 1g/1mL for class 6.1 packing group I or II, and up to 25g/25ml for all other HazMat items.

Type HazMat fee for 500 gram (Estimated)
Excepted Quantity USD 0.00
Limited Quantity USD 15-60
Inaccessible (Haz class 6.1), Domestic USD 80+
Inaccessible (Haz class 6.1), International USD 150+
Accessible (Haz class 3, 4, 5 or 8), Domestic USD 100+
Accessible (Haz class 3, 4, 5 or 8), International USD 200+
Chemical Structure| 845272-21-1
Chemical Structure| 845272-21-1
Structure of 845272-21-1 * Storage: {[proInfo.prStorage]}
Cart0 Add to My Favorites Add to My Favorites Bulk Inquiry Inquiry Add To Cart

Quality Control of [ 845272-21-1 ]

Related Doc. of [ 845272-21-1 ]

Alternatived Products of [ 845272-21-1 ]

Product Details of [ 845272-21-1 ]

CAS No. :845272-21-1 MDL No. :MFCD20275099
Formula : C22H19ClN6O2S Boiling Point : -
Linear Structure Formula :- InChI Key :-
M.W : 466.94 Pubchem ID :-
Synonyms :
ARRY-334543;ASLAN001
Chemical Name :(R)-N4-(3-Chloro-4-(thiazol-2-ylmethoxy)phenyl)-N6-(4-methyl-4,5-dihydrooxazol-2-yl)quinazoline-4,6-diamine

Safety of [ 845272-21-1 ]

Signal Word:Danger Class:9
Precautionary Statements:P280-P305+P351+P338+P310 UN#:3077
Hazard Statements:H318-H400 Packing Group:
GHS Pictogram:

Application In Synthesis of [ 845272-21-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 845272-21-1 ]

[ 845272-21-1 ] Synthesis Path-Downstream   1~8

  • 2
  • [ 851545-78-3 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: zinc; hydrogen / ethanol / 4 h 2: caesium carbonate / N,N-dimethyl-formamide / 100 °C 3: zinc; hydrogen / ethanol / 4 h 4: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
  • 3
  • [ 851545-79-4 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: caesium carbonate / N,N-dimethyl-formamide / 100 °C 2: zinc; hydrogen / ethanol / 4 h 3: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
  • 4
  • [ 1012041-42-7 ]
  • [ 2468233-85-2 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
70% With copper(l) iodide; caesium carbonate In N,N-dimethyl-formamide at 100℃; 1 Above obtained compound 21g (0.05mol) and intermediate III 5.97g (0.05mol) of cuprous iodide 0.95g, 16.25 with cesium carbonate in DMF 25ml dissolved raised to 100°C the reaction, TLC monitoring.After the reaction was completed, three times the volume of water was added to precipitate a large amount of light yellow solid, which was dissolved in ethyl acetate after suction filtration.The ethyl acetate was dried with anhydrous sodium sulfate and then distilled under reduced pressure, and the n-hexane was recrystallized to obtain 18.86 g of white solid with a yield of 70%.
  • 5
  • [ 616-79-5 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 5 steps 1: ethanol / 60 °C 2: N,N-dimethyl-formamide; benzene-1,3,5-tricarboxylic acid / tetrahydrofuran / -10 - 60 °C 3: caesium carbonate / N,N-dimethyl-formamide / 100 °C 4: zinc; hydrogen / ethanol / 4 h 5: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
  • 6
  • [ 6943-17-5 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 4 steps 1: N,N-dimethyl-formamide; benzene-1,3,5-tricarboxylic acid / tetrahydrofuran / -10 - 60 °C 2: caesium carbonate / N,N-dimethyl-formamide / 100 °C 3: zinc; hydrogen / ethanol / 4 h 4: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
  • 7
  • [ 19815-16-8 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 3 steps 1: caesium carbonate / N,N-dimethyl-formamide / 100 °C 2: zinc; hydrogen / ethanol / 4 h 3: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
  • 8
  • [ 619-08-9 ]
  • [ 845272-21-1 ]
YieldReaction ConditionsOperation in experiment
Multi-step reaction with 5 steps 1: triethylamine / 1,4-dioxane / 65 °C 2: zinc; hydrogen / ethanol / 4 h 3: caesium carbonate / N,N-dimethyl-formamide / 100 °C 4: zinc; hydrogen / ethanol / 4 h 5: caesium carbonate; copper(l) iodide / N,N-dimethyl-formamide / 100 °C
Same Skeleton Products
Historical Records