Chemistry Heterocyclic Building Blocks Purines

Purines

Purine, a heterocyclic aromatic organic compound formed by the fusion of two rings (pyrimidine and imidazole), is capable of dissolving in water.

Purines, in addition to their crucial functions in DNA and RNA as adenine and guanine, are also significant constituents of several other important biomolecules, including ATP, GTP, cyclic AMP, NADH, and coenzyme A.

The body metabolizes purines, a prevalent chemical compound present in food and beverages, converting them into uric acid, which is subsequently eliminated from the bloodstream by the kidneys.

The ability to perform de novo biosynthesis of purines is present in organisms belonging to the three domains of life, namely eukaryotes, bacteria, and archaea, underscoring the vital importance of purines for sustaining life.

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Framework+−

(R)-N-(9-(tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide 2-(acetoxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 2-(hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 2-chloro-7H-purine 2-chloro-9H-purine 7H-purin-2-amine 7H-purin-6-amine 9-((3aS,4R,6aR)-tetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purine 9-(tetrahydrofuran-2-yl)-9H-purin-6-amine 9-(tetrahydrofuran-2-yl)-9H-purin-6-ol 9-(tetrahydrofuran-2-yl)-9H-purine 9H-purin-6-amine

By Key Group+−

amino-purin chloro-purine hydroxy-purine purin-one

By Parent Nucleus+−

Aromatic Heterocycles Other Aromatic Heterocycles Pyridines Tetrahydrofurans Thiophenols

By Functional Group+−

Alcohols Alkenyls Alkynyls Amides Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Ketones Nitriles Phenols Phosphoruses Sulfides

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    2′-O-Methyl-8-methyl guanosine

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    Bemnifosbuvir

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    6-Chloro-2-propyl-9H-purine

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    6-Chloro-2-propyl-9H-purine

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    SQ22536

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    SQ22536

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    2-Chloro-9H-purine

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    N-(8-Bromo-6-oxo-6,9-dihydro-1H-purin-2-yl)pivalamide

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    Acyclovir

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    Acyclovir

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    ATP disodium salt

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    ATP disodium salt

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    N-Carbobenzyloxy-L-valinyl-ganciclovir

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    Entecavir

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    Entecavir

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    Adenosine

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    Adenosine

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    Adenosine 5'-diphosphate sodium salt

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    2′,3′-Isopropylideneinosine

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    2′,3′-Isopropylideneinosine

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    L-Guanosine

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    2',3'-Dideoxyinosine

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    6-Chloro-2-fluoro-9-isopropyl-9H-purine

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    $451.00/1g

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    6-Isopropoxy-1H-purin-2-amine

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    6-Isopropoxy-1H-purin-2-amine

    $176.00/250mg

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    ATP

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    ATP

    $19.00/10g

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    LysRs-IN-1

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    LysRs-IN-1

    $579.00/100mg

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    Acyclovir

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    Acyclovir

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