Home Chemistry Heterocyclic Building Blocks Pyridines Pyridin-4-Amine
Acetylation: It can undergo acetylation reactions, where an acetyl group (-COCH3) replaces the amino hydrogen. This reaction is commonly employed in organic synthesis to introduce acetyl groups onto the amine.
Acylation: Pyridin-4-amine can undergo acylation reactions, where various acyl groups can be introduced onto the amino nitrogen. This reaction is similar to acetylation but can involve other acyl groups besides acetyl.
Nitration: Pyridin-4-amine can undergo nitration reactions, where a nitro group (-NO2)substitutes one of the hydrogen atoms on the aromatic ring. Nitration is often carried out under controlled conditions using nitrating agents such as nitric acid or a mixture of nitric and sulfuric acids.
Alkylation and Arylation: Pyridin-4-amine can undergo alkylation or arylation reactions, where alkyl or aryl groups are introduced onto the amino nitrogen or the aromatic ring. These reactions are often employed in the synthesis of various organic compounds.
Reduction: Pyridin-4-amine can undergo reduction reactions, where the amino group (-NH2) or the nitro group (-NO2)can be reduced to form corresponding products. Reduction reactions are often carried out using reducing agents such as hydrogen gas in the presence of a catalyst or with metal hydrides.
Halogenation: Pyridin-4-amine can undergo halogenation reactions, where halogen atoms (such as chlorine, bromine, or iodine) are introduced onto the aromatic ring. Halogenation can occur under suitable conditions using halogenating agents.
Substitution reactions: Pyridin-4-amine can undergo various substitution reactions, where functional groups or atoms on the molecule are replaced by other functional groups or atoms. These substitution reactions can be carried out using appropriate reagents and conditions.
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2-(4-Aminopyridin-2-yl)-2-methylpropanenitrile
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