Home Chemistry Heterocyclic Building Blocks Pyrrolidines Pyrrolidine-2-Carbonitrile
Hydrolysis: Under acidic or basic conditions, the nitrile group (-CN) can undergo hydrolysis to form the corresponding carboxylic acids or carboxylic acid derivative.
Reduction: The nitrile group can be reduced to form the corresponding primary amine using reducing agents like lithium aluminum hydride or hydrogenation catalysts.
Substitution Reactions: The carbon atom of the nitrile group can undergo substitution reactions, such as nucleophilic substitution or electrophilic substitution.
Acylation: The nitrogen atom in the pyrrolidine ring can undergo acylation reactions to form N-acyl derivatives.
Ring-opening Reactions: The pyrrolidine ring may undergo ring-opening reactions under certain conditions, leading to the formation of linear or branched compounds.
Condensation Reactions: It can participate in condensation reactions to form cyclic compounds or larger molecules.
Oxidation: The carbon atom adjacent to the nitrile group can be oxidized to form a carboxylic acid or carboxylic acid derivative.
Alkylation: The nitrogen atom can be alkylated by reaction with alkyl halides or sulfonatesl.
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(2S,4S)-4-Fluoropyrrolidine-2-carbonitrile hydrochloride
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(S)-2-Pyrrolidinecarbonitrile hydrochloride
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tert-Butyl 2-cyanopyrrolidine-1-carboxylate
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(R)-(+)-1-Boc-2-pyrrolidinecarbonitrile
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(R)-Pyrrolidine-2-carbonitrile hydrochloride
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(S)-1-(2-Chloroacetyl)pyrrolidine-2-carbonitrile
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(S)-tert-Butyl 2-cyanopyrrolidine-1-carboxylate
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(S)-4,4-Difluoropyrrolidine-2-carbonitrile hydrochloride
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