Home Chemistry Heterocyclic Building Blocks Piperidines Spiro[Indoline-3,4'-Piperidin]-2-One
Nucleophilic Substitution Reactions: If there are suitable leaving groups (e.g., halides) present, nucleophiles can attack the electrophilic carbon centers, leading to substitution reactions.
Reduction Reactions: The ketone functionality (C=O) in spiro[indoline-3,4'-piperidin]-2-one can be reduced to an alcohol (C-OH) using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Acid-Base Reactions: The basic nitrogen atoms in the indoline and piperidine rings can act as Lewis bases, potentially participating in acid-base reactions.
Cyclization Reactions: Depending on the conditions, the compound may undergo intramolecular cyclization reactions to form different ring systems or rearrange into other isomeric forms.
Oxidation Reactions: Under appropriate conditions, the compound may undergo oxidation, potentially converting functional groups into different oxidation states.
Grignard Reactions: If there are appropriate electrophiles, the compound may react with Grignard reagents to form new carbon-carbon bonds.
Condensation Reactions: If there are suitable reactants, the ketone functionality could participate in condensation reactions, forming C-C or C-N bonds.
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Spiro[indoline-3,4'-piperidin]-2-one hydrochloride
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tert-Butyl 5-bromo-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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5-Nitrospiro[indoline-3,4'-piperidin]-2-one hydrochloride
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tert-Butyl 7-fluoro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 6-methoxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 6-hydroxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 6-fluoro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 5-methyl-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 4-fluoro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 4-chloro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 5-chloro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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tert-Butyl 5-methoxy-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
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1'-Boc-1,2-dihydro-2-oxo-spiro[3H-indole-3,4'-piperidine]
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