Chemistry Organic Building Blocks Sulfonyl Chlorides
The ease with which sulfonyl chlorides can react with heterocyclic amines to form intricate sulfonamide compounds makes them a favored choice of building blocks in medicinal chemistry.
The sulfonyl chlorides and fluorides are the most important, with the stability of sulfonyl halides decreasing in the following order: fluorides > chlorides > bromides > iodides.
Sulfonyl chlorides, also known as sulfonic acid chlorides, have a general formula of RSO2Cl and belong to the class of sulfonyl halides.
Benzenesulfonyl chloride is a derivative that holds significance in industry, while in the laboratory, reagents such as tosyl chloride, brosyl chloride, nosyl chloride, and mesyl chloride prove to be useful.
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2-Cyano-4-fluorobenzene-1-sulfonyl chloride
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2-Bromo-5-(trifluoromethyl)benzene-1-sulfonyl chloride
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5-(Methylcarbamoyl)thiophene-3-sulfonyl chloride
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4-(2-Methoxyethoxy)benzenesulfonyl chloride
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3,5-Dichloro-4-(2-(dimethylamino)-2-oxoethoxy)benzenesulfonyl chloride
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2-Chloro-5-cyanobenzene-1-sulfonyl chloride
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3-Bromo-4-chlorobenzene-1-sulfonyl chloride
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2-Chloro-4-cyanobenzene-1-sulfonyl chloride
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4-Bromo-3-cyanobenzene-1-sulfonyl chloride
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4-(Dimethylamino)benzene-1-sulfonyl chloride
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3-Bromo-2-methylbenzene-1-sulfonyl chloride
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4-Nitro-3-(trifluoromethyl)benzenesulfonyl chloride