Home Chemistry Heterocyclic Building Blocks Indazoles Tert-Butyl 1H-Indazole-1-Carboxylate
Nucleophilic Substitution: The carboxylate group can undergo nucleophilic substitution reactions with various electrophiles, leading to the formation of substituted carboxylates.
Ester Hydrolysis: The ester group can undergo hydrolysis under acidic or basic conditions to form the corresponding carboxylic acid and alcohol.
Reduction: The carbonyl group of the ester can be reduced to the corresponding alcohol using reducing agents such as lithium aluminum hydride or sodium borohydride.
Acylation: The nitrogen atom in the indazole ring can undergo acylation reactions to form N-acyl derivatives.
Substitution Reactions: The indazole ring can undergo substitution reactions, such as nucleophilic aromatic substitution or electrophilic aromatic substitution, depending on the reaction conditions and reagents used.
Ring-closure Reactions: It can participate in ring-closure reactions to form fused ring systems or other cyclic compounds.
Oxidation: Under suitable conditions, oxidation reactions can occur to convert the alcohol group to the corresponding carbonyl compound or carboxylic acid.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
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tert-Butyl 3-methyl-5-nitro-1H-indazole-1-carboxylate
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tert-Butyl 6-hydroxy-1H-indazole-1-carboxylate
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tert-Butyl 5-nitro-1H-indazole-1-carboxylate
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1-tert-Butyl 5-methyl 1H-indazole-1,5-dicarboxylate
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tert-Butyl 5-amino-1H-indazole-1-carboxylate
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tert-Butyl 5-(trifluoromethoxy)-1H-indazole-1-carboxylate
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tert-Butyl 4-amino-1H-indazole-1-carboxylate
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tert-Butyl 5-bromo-1H-indazole-1-carboxylate
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1-tert-Butyl 6-methyl 1H-indazole-1,6-dicarboxylate
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tert-Butyl 6-bromo-4-methoxy-1H-indazole-1-carboxylate
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tert-Butyl 5-bromo-3-methyl-1H-indazole-1-carboxylate
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tert-Butyl 5-amino-3-methyl-1H-indazole-1-carboxylate
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tert-Butyl 3-iodo-7-methoxy-1H-indazole-1-carboxylate
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tert-Butyl 5-hydroxy-3-iodo-1H-indazole-1-carboxylate
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tert-Butyl 5-((tert-butyldimethylsilyl)oxy)-3-iodo-1H-indazole-1-carboxylate
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tert-Butyl 3-iodo-1H-indazole-1-carboxylate
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tert-Butyl 3-amino-1H-indazole-1-carboxylate
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tert-Butyl 7-bromo-1H-indazole-1-carboxylate
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