Chemistry Heterocyclic Building Blocks Tetrahydroquinolines

Tetrahydroquinolines

An organic compound known as tetrahydroquinoline, which is a partially hydrogenated form of quinoline, exists as a colorless oil.

Quinolines can be hydrogenated to produce tetrahydroquinolines, which are commonly studied as a hydrogen-donor solvent in coal liquefaction due to the reversible nature of the hydrogenation process.

1,2,3,4-Tetrahydroquinoline serves as an antioxidant and corrosion inhibitor, and also functions as an active ingredient in several dyes.

Medicinal chemistry often utilizes substituted derivatives of tetrahydroquinoline, which include bioactive compounds such as oxamniquine, dynemycin, viratmycin, and nicainoprol.

Heterogeneous catalysts are typically used to prepare tetrahydroquinoline derivatives through the hydrogenation of the corresponding quinoline.

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Framework+−

1-ethyl-1,2,3,4-tetrahydroquinoline 1-methyl-1,2,3,4-tetrahydroquinoline 2,3-dihydroquinolin-4(1H)-one 2-methyl-1,2,3,4-tetrahydroquinoline 4,4-dimethyl-1,2,3,4-tetrahydroquinoline 4-methyl-1,2,3,4-tetrahydroquinoline 5,6,7,8-tetrahydroquinoline 6-bromo-1,2,3,4-tetrahydroquinoline 6-chloro-1,2,3,4-tetrahydroquinoline 6-fluoro-1,2,3,4-tetrahydroquinoline 7-fluoro-1,2,3,4-tetrahydroquinoline tert-butyl 3,4-dihydroquinoline-1(2H)-carboxylate

By Key Group+−

hydroxy-tetrahydroquinoline other-tetrahydroquinoline tetrahydroquinolin-amine tetrahydroquinoline-benzene tetrahydroquinoline-bromide tetrahydroquinoline-carbonitrile tetrahydroquinoline-carboxylate tetrahydroquinoline-carboxylic acid tetrahydroquinoline-carboxylic-acid tetrahydroquinoline-chloride tetrahydroquinoline-fluoro tetrahydroquinoline-hydrochloride tetrahydroquinoline-methoxy tetrahydroquinoline-methyl tetrahydroquinoline-nitro

By Parent Nucleus+−

Aromatic Heterocycles Pyridines Quinolines Spiroes Tetrahydroisoquinolines

By Functional Group+−

Alcohols Amides Amines Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Ketones Nitriles Nitroes Phenols Sulfamides

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    1-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroquinoline-7-carboxylic acid

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    A288414928772-51-496%

    1-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroquinoline-7-carboxylic acid

    $370.00/250mg

    Detail
    7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one

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    A740878120004-79-797%

    7-(4-Chlorobutoxy)-3,4-dihydroquinolin-2(1H)-one

    $64.00/250mg

    Detail
    6-Bromo-4-methyl-1,2,3,4-tetrahydroquinoline

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    A129173946837-99-697%

    6-Bromo-4-methyl-1,2,3,4-tetrahydroquinoline

    $29.00/100mg

    Detail
    8-Chloro-3,4-dihydroquinolin-2(1H)-one

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    A31752883229-23-695%

    8-Chloro-3,4-dihydroquinolin-2(1H)-one

    $149.00/1g

    Detail
    3-Amino-1-methyl-3,4-dihydroquinolin-2(1H)-one

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    A674228403860-64-095%

    3-Amino-1-methyl-3,4-dihydroquinolin-2(1H)-one

    $167.00/100mg

    Detail
    5-Chloro-2,3-dihydroquinolin-4(1H)-one

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    A39933221617-16-395%

    5-Chloro-2,3-dihydroquinolin-4(1H)-one

    $447.00/1g

    Detail
    6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

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    A671175400620-72-698%

    6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

    $29.00/100mg

    Detail
    6-(tert-Butyl)-3,4-dihydroquinolin-2(1H)-one

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    A10059141198764-90-797%

    6-(tert-Butyl)-3,4-dihydroquinolin-2(1H)-one

    $157.00/250mg

    Detail
    1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

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    A2345171427587-32-395%

    1-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,4-dihydroquinolin-2(1H)-one

    $46.00/1g

    Detail
    8-Amino-3,4-dihydroisoquinolin-1(2H)-one

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    A210196169045-00-595%

    8-Amino-3,4-dihydroisoquinolin-1(2H)-one

    $1016.00/1g

    Detail
    6-Amino-8-fluoro-3,4-dihydroquinolin-2(1H)-one

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    A588166113225-70-098%

    6-Amino-8-fluoro-3,4-dihydroquinolin-2(1H)-one

    $1248.00/1g

    Detail
    6-Bromo-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid

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    A1063110264276-41-795%

    6-Bromo-2-oxo-1,2,3,4-tetrahydroquinoline-4-carboxylic acid

    $153.00/50mg

    Detail
    5,6,7,8-Tetrahydroquinolin-8-amine

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    A267773298181-83-696%

    5,6,7,8-Tetrahydroquinolin-8-amine

    $133.00/250mg

    Detail
    7-Nitro-3,4-dihydroisoquinolin-1(2H)-one

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    A16590822245-96-198%

    7-Nitro-3,4-dihydroisoquinolin-1(2H)-one

    $532.00/5g

    Detail
    Methyl 2-methoxy-6-oxo-5,6,7,8-tetrahydroquinoline-5-carboxylate

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    A454839130518-34-297%

    Methyl 2-methoxy-6-oxo-5,6,7,8-tetrahydroquinoline-5-carboxylate

    $353.00/5g

    Detail
    6-Bromo-1-methyl-3,4-dihydroquinolin-2(1H)-one

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    A4094451092523-03-995%

    6-Bromo-1-methyl-3,4-dihydroquinolin-2(1H)-one

    $97.00/5g

    Detail
    5-Bromo-1,2,3,4-tetrahydroquinoline

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    A200491114744-50-297%

    5-Bromo-1,2,3,4-tetrahydroquinoline

    $372.00/25g

    Detail
    1,2,3,4-Tetrahydroquinoline-7-carboxylic acid

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    A68726222048-88-098%

    1,2,3,4-Tetrahydroquinoline-7-carboxylic acid

    $143.00/100mg

    Detail
    1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one

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    A1217808851274-39-098%

    1-(3,4-Dihydroquinolin-1(2H)-yl)-2-((4-(2-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)ethan-1-one

    $477.00/250mg

    Detail
    1-Ethyl-6-fluoro-1,2,3,4-tetrahydroquinoline

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    A258297209336-49-297%

    1-Ethyl-6-fluoro-1,2,3,4-tetrahydroquinoline

    $36.00/1g

    Detail
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