Chemistry Organic Building Blocks Thiols
In the field of organic chemistry, a thiol, or a thiol derivative, is a type of organosulfur compound with the general formula R−SH, where R represents an alkyl or another type of organic substituent. The functional group −SH is commonly known as a thiol group, a sulfhydryl group, or a sulfanyl group.
Thiols are organic compounds that serve as the sulfur analogue of alcohols, where sulfur replaces oxygen in the hydroxyl (−OH) group of an alcohol. The term "thiol" is derived from a combination of "thio-" and "alcohol", reflecting this substitution of oxygen with sulfur in the functional group.
Organic compounds with the structure R−SH are commonly known as alkanethiols or alkyl thiols, where an alkyl group (R) is attached to a sulfhydryl group (SH).
Compared to their corresponding alcohols, thiols exhibit a lower dipole moment.
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