Chemistry Heterocyclic Building Blocks Triazines

Triazines

Nitrogen-containing heterocycles known as triazines have a molecular formula of C3H3N3 and can exist in three isomeric forms, with 1,3,5-triazines being a commonly occurring isomer.

Triazines are characterized by a flat ring with six members that resembles benzene, except for the replacement of three carbon atoms with nitrogen. The triazine's three isomers are named based on the locations of their nitrogen atoms and are denoted as 1,2,3-triazine, 1,2,4-triazine, and 1,3,5-triazine.

Despite being aromatic compounds, triazines have a much lower resonance energy than benzene. While electrophilic aromatic substitution is challenging for them, nucleophilic aromatic substitution is easier compared to typical chlorinated benzenes.

Triazine and its derivatives have a wide range of commercial applications, including use in resins, dyes, herbicides, and as agents for removing sulfides. As a prototypal molecule, triazine has played a key role in the development of these industries.

GC-NPD can be used for direct analysis of triazines, while LC-UV DAD is also capable of analyzing them easily. The two methods yield detection limits that are roughly comparable due to the strong absorbance of triazines at 220 nm, though LC-UV reportedly has lower sensitivity than GC-NPD.

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Framework+−

1,2,4-triazine 1,3,5-triazin-2-amine 2,4,6-triphenoxy-1,3,5-triazine 2,4,6-triphenyl-1,3,5-triazine 2,4-diphenyl-1,3,5-triazine 2-chloro-1,3,5-triazine 2-methoxy-1,3,5-triazine 2-phenyl-1,3,5-triazine N2,N4,N6-triphenyl-1,3,5-triazine-2,4,6-triamine pyrrolo[2,1-f][1,2,4]triazine

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amino-triazine benzotriazine methyl-triazine other-triazine phenyl-triazine pyrazolotriazine pyridyl-triazine triazin-amine triazine-one

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Aromatic Heterocycles Imidazoles Morpholines Other Aliphatic Heterocycles Pyridines

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Alcohols Alkenyls Amides Amines Aryls Bromides Carboxylic Acid Salts Carboxylic Acids Chiral Building Blocks Chlorides Ethers Fluorinated Building Blocks Hydrazines Phenols Sulfides Trifluoromethyls

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    3-Amino-6-(aminomethyl)-1,2,4-triazin-5(4H)-one acetate

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    A2536411353100-80-797%

    3-Amino-6-(aminomethyl)-1,2,4-triazin-5(4H)-one acetate

    $86.00/1g

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    5-Propyl-5H-[1,2,4]triazino[5,6-b]indole-3-thiol

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    A109105836047-56-095%

    5-Propyl-5H-[1,2,4]triazino[5,6-b]indole-3-thiol

    $257.00/1g

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    1,2,4-Triazin-5-amine

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    A765972822-69-598%

    1,2,4-Triazin-5-amine

    $1040.00/1g

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    2-(4-Biphenylyl)-4,6-dichloro-1,3,5-triazine

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    A62385410202-45-698%

    2-(4-Biphenylyl)-4,6-dichloro-1,3,5-triazine

    $19.00/5g

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    Ethyl pyrrolo[2,1-f][1,2,4]triazine-7-carboxylate

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    A7167721356016-44-897%

    Ethyl pyrrolo[2,1-f][1,2,4]triazine-7-carboxylate

    $79.00/50mg

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    Sodium (6R,7R)-7-amino-3-(((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

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    A164463131257-07-397%

    Sodium (6R,7R)-7-amino-3-(((6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

    $65.00/5g

    Detail
    N2,N4,N6-Tris(2-aminoethyl)-1,3,5-triazine-2,4,6-triamine 2,2,2-trifluoroacetate(1:x)

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    A14928582253121-62-797%

    N2,N4,N6-Tris(2-aminoethyl)-1,3,5-triazine-2,4,6-triamine 2,2,2-trifluoroacetate(1:x)

    $100.00/250mg

    Detail
    3-Iodo-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine

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    A8130921383675-85-195%

    3-Iodo-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine

    $1271.00/5g

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    4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile

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    A8664941197377-47-195%

    4-(3-Amino-1,2,4-triazin-6-yl)-2-fluorobenzonitrile

    $75.00/1g

    Detail
    2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

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    A105984864377-31-197%

    2-(3-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

    $6.00/1g

    Detail
    5-tert-Butyl-1,2,4-triazin-3-amine

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    A1117902937-02-095%

    5-tert-Butyl-1,2,4-triazin-3-amine

    $63.00/250mg

    Detail
    Meladrazine

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    A22786313957-36-396%

    Meladrazine

    $101.00/25mg

    Detail
    1,3,5-Tributyl-1,3,5-triazinane-2,4,6-trione

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    A1492261846-74-295%

    1,3,5-Tributyl-1,3,5-triazinane-2,4,6-trione

    $458.00/100mg

    Detail
    2-Chloro-4-methyl-6-phenyl-1,3,5-triazine

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    A122910930937-70-397%

    2-Chloro-4-methyl-6-phenyl-1,3,5-triazine

    $120.00/100mg

    Detail
    SIRT2-IN-9

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    A1229239522650-91-598%

    SIRT2-IN-9

    $666.00/50mg

    Detail
    Allantoxanamide

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    A59298669391-08-895%

    Allantoxanamide

    $207.00/250mg

    Detail
    2-(2-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

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    A75700177989-15-299%

    2-(2-Bromophenyl)-4,6-diphenyl-1,3,5-triazine

    $22.00/5g

    Detail
    3,5,6-Trichloro-1,2,4-triazine

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    A543549873-41-698%

    3,5,6-Trichloro-1,2,4-triazine

    $325.00/25g

    Detail
    N2,N4,N6-Trimethyl-1,3,5-triazine-2,4,6-triamine

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    A11272852827-46-595%

    N2,N4,N6-Trimethyl-1,3,5-triazine-2,4,6-triamine

    $569.00/5g

    Detail
    6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine

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    A63309238668-46-198%

    6-(2-(2-Methyl-1H-imidazol-1-yl)ethyl)-1,3,5-triazine-2,4-diamine

    $5.00/5g

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