Chemistry Heterocyclic Building Blocks Benzofurans

Benzofurans

Benzofuran, a colorless liquid present in coal tar, is a heterocyclic compound that comprises fused benzene and furan rings. It serves as the precursor of numerous related compounds with more intricate structures.

Benzofurans exhibit a low degree of aromaticity and are susceptible to cleavage under various oxidative and reductive conditions. Additionally, concentrated mineral acids and Lewis acids can induce their polymerization.

Benzofuran, a fused ring system of benzene and furan, is an important oxygen-containing heterocycle with potent biological properties. It is widely found in naturally occurring and synthetically derived compounds and exhibits antifungal, antibacterial, antiviral, and anti-inflammatory activities.

Benzofurans that have been substituted are utilized in a variety of fields including drug discovery, chemistry, agriculture, and as fluorescent sensors and oxidants.

Benzofuran derivatives, which are oxygen-containing heterocycles, hold significant importance. Compounds containing benzofuran skeletons, whether naturally occurring or artificially synthesized, have demonstrated exceptional activity as pharmaceuticals and agrochemicals.

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Framework+−

1-(benzofuran-2-yl)ethan-1-one 2,2-dimethyl-2,3-dihydrobenzofuran 2,3-dihydrobenzofuran-3-amine 2,3-dihydrobenzofuran-5-amine 2,3-dihydrobenzofuran-7-amine 2-(benzofuran-3-yl)acetic acid 2-bromodibenzo[b,d]furan 2-ethylbenzofuran 2-methylbenzofuran 3-methylbenzofuran 4-bromobenzofuran 4-phenyldibenzo[b,d]furan 5,7,8-trimethylchromane 5-bromo-2,3-dihydrobenzofuran 5-chloro-2,3-dihydrobenzofuran 5-fluoro-2,3-dihydrobenzofuran 5-methoxyisobenzofuran-1(3H)-one 6-bromo-2,3-dihydrobenzofuran 6-fluoro-2,3-dihydrobenzofuran 6-methoxybenzofuran 7-bromo-2,3-dihydrobenzofuran 7-bromobenzofuran 7-fluoro-2,3-dihydrobenzofuran benzofuran-2(3H)-one benzofuran-2-carbaldehyde benzofuran-2-carboxylic acid benzofuran-2-ylboronic acid benzofuran-3(2H)-one benzofuran-3-carboxylic acid benzofuran-3-yl(phenyl)methanone methyl benzofuran-2-carboxylate

By Key Group+−

aminobenzofuran aminofuro benzofuran-amine benzofuran-boronic acid benzofuran-carbonitrile benzofuran-carboxylate benzofuran-carboxylic acid benzofuran-dioxaborolane benzofuran-hydrochloride benzofuran-methanol benzofuran-one benzofuranocarbazole benzofuranopyrimidine bromobenzofuran bromoisobenzofuran chlorobenzofuran chloroisobenzofuran dihydrobenzofuran dihydroisobenzofuran dimethoxyisobenzofuran epoxyisobenzofuran ethylbenzofuran fluorobenzofuran fluoroisobenzofuran hexahydroisobenzofuran hydroxy-benzofuran hydroxybenzofuran hydroxyisobenzofuran iodo-benzofuran iodoisobenzofuran isobenzofuran methoxybenzofuran methoxyisobenzofuran methylbenzofuran methylbenzofuro methylisobenzofuran nitrobenzofuran nitroisobenzofuran other benzofuran phenyl-benzofuran piperidine-benzofuran spiro-benzofuran-piperidine tetrahydrobenzofuran

By Parent Nucleus+−

Aromatic Heterocycles Indoles Other Aromatic Heterocycles Piperazines Piperidines Spiroes

By Functional Group+−

Alcohols Aldehydes Alkenyls Amides Amines Anhydrides Aryls Bromides Carboxylic Acids Chiral Building Blocks Chlorides Esters Ethers Fluorinated Building Blocks Iodides Ketones Nitriles Nitroes Organoboron Phenols Sulfamides Sulfonyl Chlorides

By Chemical Elements+−

    Bx
    Cx
    Nx
    Ox
    Fx
    Six
    Px
    Sx
    Clx
    Brx
    Ix

    Formula Weight+−

    cLogP+−

    H-Acceptors+−

    H-Donors+−

    Polar Surface Area+−

    Druglikeness+−

    NNCH/NNH+−

    sp3-Atoms+−

    Non-Aromatic Rings+−

    Aromatic Rings+−

    Rotatable Bonds+−

    By Configuration+−

    Ethyl 6-methoxy-3-phenylbenzofuran-2-carboxylate

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    A144099858468-42-197%

    Ethyl 6-methoxy-3-phenylbenzofuran-2-carboxylate

    $25.00/100mg

    Detail
    6-Methoxy-3(2H)-benzofuranone

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    A15241915832-09-498%

    6-Methoxy-3(2H)-benzofuranone

    $65.00/250mg

    Detail
    Ethyl 6-bromobenzofuran-3-carboxylate

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    A5439721260799-56-195%

    Ethyl 6-bromobenzofuran-3-carboxylate

    $47.00/250mg

    Detail
    5-Iodoisobenzofuran-1,3-dione

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    A21769828418-89-598%

    5-Iodoisobenzofuran-1,3-dione

    $34.00/100mg

    Detail
    2-Bromo-8-chlorodibenzo[b,d]furan

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    A14961351360145-45-498%

    2-Bromo-8-chlorodibenzo[b,d]furan

    $38.00/100mg

    Detail
    Methyl 7-amino-2,2-dimethyl-2,3-dihydrobenzofuran-4-carboxylate

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    A16461301280665-90-898%

    Methyl 7-amino-2,2-dimethyl-2,3-dihydrobenzofuran-4-carboxylate

    $1575.00/1g

    Detail
    3-Aminobenzofuran-2-carboxamide

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    A13450154802-10-795%

    3-Aminobenzofuran-2-carboxamide

    $16.00/1g

    Detail
    5-Bromo-7-methoxybenzofuran-2-carboxylic acid

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    A67393120037-37-095%

    5-Bromo-7-methoxybenzofuran-2-carboxylic acid

    $113.00/1g

    Detail
    (2,3-Dihydrobenzofuran-5-yl)methanol

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    A134899103262-35-798%

    (2,3-Dihydrobenzofuran-5-yl)methanol

    $30.00/250mg

    Detail
    Salvianolic acid B

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    A179169121521-90-298%

    Salvianolic acid B

    $188.00/250mg

    Detail
    7-Formyl-1-benzofuran-2-carboxylic acid

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    A10485701782910-29-595%

    7-Formyl-1-benzofuran-2-carboxylic acid

    $1013.00/1g

    Detail
    Benzofuran-6-carboxylic acid

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    A25585277095-51-398%

    Benzofuran-6-carboxylic acid

    $14.00/1g

    Detail
    1,3-Dioxo-1,3-dihydroisobenzofuran-4-carboxylic acid

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    A6587673786-39-897%

    1,3-Dioxo-1,3-dihydroisobenzofuran-4-carboxylic acid

    $605.00/1g

    Detail
    L-3373

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    A8552761951-26-498%

    L-3373

    $576.00/5g

    Detail
    (5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine

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    A11467221896262-04-698%

    (5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine

    $61.00/250mg

    Detail
    Methyl 1-oxo-1,3-dihydroisobenzofuran-5-carboxylate

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    A22272423405-32-595%

    Methyl 1-oxo-1,3-dihydroisobenzofuran-5-carboxylate

    $67.00/10g

    Detail
    (5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine hydrochloride

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    A12574752135600-87-097%

    (5-Fluoro-2,3-dihydrobenzofuran-4-yl)methanamine hydrochloride

    $58.00/250mg

    Detail
    3-Methoxyisobenzofuran-1(3H)-one

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    A6302214122-57-098%

    3-Methoxyisobenzofuran-1(3H)-one

    $112.00/5g

    Detail
    3-Propylideneisobenzofuran-1(3H)-one

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    A13234117369-59-496% mixture of cis and trans isomers

    3-Propylideneisobenzofuran-1(3H)-one

    $347.00/500g

    Detail
    4-Nitro-1,3-dihydroisobenzofuran

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    A40320098475-08-295%

    4-Nitro-1,3-dihydroisobenzofuran

    $538.00/1g

    Detail
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