Home Chemistry Organic Building Blocks Trifluoromethyls Methyl 2-(Trifluoromethyl)Benzoate
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —CF3,—COOCH3).
Friedel-Crafts Acylation/Alkylation: The (trifluoromethyl)benzene can undergo Friedel-Crafts acylation or alkylation reactions, in which an acyl or alkyl group is added to the benzene ring. These reactions are catalyzed by Lewis acids and result in the formation of new carbon-carbon bonds.
Hydrolysis: Methyl benzoate can undergo hydrolysis in the presence of water and a catalytic amount of acid or base, yielding methanol and benzoic acid. This reaction involves breaking the ester bond and forming the corresponding 【carboxylic acid|https://www.ambeed.com/carboxylic-acids.html】 and 【alcohol|https://www.ambeed.com/alcohol.html】.
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Methyl 4-fluoro-2-(trifluoromethyl)benzoate
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Methyl 4-methoxy-2-(trifluoromethyl)benzoate
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(4-(Methoxycarbonyl)-3-(trifluoromethyl)phenyl)boronic acid
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Methyl 4-nitro-2-(trifluoromethyl)benzoate
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Methyl 5-amino-2-(trifluoromethyl)benzoate
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Methyl 5-nitro-2-(trifluoromethyl)benzoate
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Methyl 4-amino-2-(trifluoromethyl)benzoate
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Methyl 4-iodo-2-(trifluoromethyl)benzoate
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Methyl 4-bromo-2-(trifluoromethyl)benzoate
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