Home Chemistry Heterocyclic Building Blocks Indazoles 4-Methoxy-1H-Indazole
Substitution Reactions: The methoxy group can undergo substitution reactions, such as nucleophilic aromatic substitution, with various electrophiles, leading to the formation of substituted indazoles.
Electrophilic Aromatic Substitution: The aromatic ring can undergo electrophilic aromatic substitution reactions with electrophiles, leading to the formation of substituted products.
Reduction: The nitro group, if present, can be reduced to the corresponding amino group using reducing agents such as hydrogen gas over a metal catalyst or iron filings and concentrated hydrochloric acid (the Zincke method).
Nucleophilic Addition: The aromatic ring can undergo nucleophilic addition reactions with strong nucleophiles under suitable conditions, leading to the formation of substituted products.
Ring-closing Reactions: It can participate in ring-closing reactions to form fused or bridged ring systems under appropriate conditions.
Heterocyclic Chemistry: It can undergo various heterocyclic chemistry reactions, such as ring-opening reactions, cyclization reactions, or functional group transformations, to form diverse heterocyclic compounds.
Oxidation: Depending on the functional groups present, oxidation reactions can occur to form various oxidized products.
Grignard Reactions: The indazole ring can react with Grignard reagents to form substituted products through nucleophilic addition reactions.
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4-Methoxy-1H-indazole-6-carboxylic acid
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