Home Chemistry Heterocyclic Building Blocks Purines (R)-N-(9-(Tetrahydrofuran-2-Yl)-9H-Purin-6-Yl)Benzamide
Acylation: The amide functional group in benzamide can undergo acylation reactions, where the amide nitrogen reacts with acyl chlorides or anhydrides to form amide derivatives.
Alkylation: The benzene ring in benzamide can undergo Friedel-Crafts alkylation or acylation reactions to introduce alkyl or acyl groups.
Nucleophilic Substitution: The tetrahydrofuran ring can be susceptible to nucleophilic substitution reactions. The purine moiety can also undergo nucleophilic substitutions at various positions.
Cyclization: Depending on reaction conditions, cyclization reactions involving the purine and tetrahydrofuran moieties might be possible.
Heterocycle Formation: Depending on the reaction conditions and reagents, heterocycle formation reactions could occur.
Esterification: The carboxamide group can be converted into an ester through reaction with appropriate reagents.
Hydrolysis: The amide group can be hydrolyzed under acidic or basic conditions to form carboxylic acid and amine derivatives.
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