Home Chemistry Heterocyclic Building Blocks Indazoles (1H-Indazol-4-Yl)Boronic Acid
Suzuki-Miyaura Coupling: (1H-indazol-4-yl)boronic acid can undergo Suzuki-Miyaura coupling reactions with aryl or vinyl halides or triflates in the presence of a palladium catalyst and a base. This reaction forms biaryl compounds.
Boronic Acid Pinacol ester Formation: (1H-indazol-4-yl)boronic acid can react with pinacol boronic ester in the presence of a suitable catalyst to form a boronate pinacol ester.
Halogenation: The boronic acid group can undergo halogenation reactions, such as bromination or chlorination, to introduce halogen atoms to the boron atom.
Oxidation: The boronic acid group can be oxidized to the corresponding boronic acid derivative, such as boronic acid ester or boronate salt, using oxidizing agents like hydrogen peroxide or sodium perborate.
Borylation: (1H-indazol-4-yl)boronic acid can undergo borylation reactions with various electrophiles, such as aryl halides or triflates, to form boron-containing compounds.
Cross-coupling Reactions: (1H-indazol-4-yl)boronic acid can participate in various cross-coupling reactions with other organic halides or pseudohalides under suitable conditions.
Metalation: (1H-indazol-4-yl)boronic acid can undergo metalation reactions, where a metal atom or group is introduced to the boron atom, leading to the formation of organoboron compounds.
Complexation: (1H-indazol-4-yl)boronic acid can form complexes with Lewis acids or other metal ions through coordination to the boron atom.
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(5-Methyl-1H-indazol-4-yl)boronic acid
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(7-Methyl-1H-indazol-4-yl)boronic acid
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