Chemistry Heterocyclic Building Blocks Quinoxalines
An organic compound known as a benzopyrazine or quinoxaline is a type of heterocyclic compound that consists of a fused ring system comprising a pyrazine ring and a benzene ring. Quinoxaline is an isomer of several other naphthyridines, such as quinazoline, phthalazine, and cinnoline.
While quinoxaline may be of primarily academic interest, its derivatives have practical applications as dyes, pharmaceuticals (e.g. varenicline), and antibiotics, including olaquindox, carbadox, echinomycin, levomycin, and actinoleutin.
Due to their broad range of biological activities, which include anti-viral, anti-bacterial, and anti-inflammatory effects, quinoxalines and their derivatives have become desirable targets in the fields of synthetic and medicinal chemistry.
Quinoxaline compounds have drawn attention due to their antitumoral properties. More recently, researchers have explored the use of quinoxaline and its analogs as ligands for catalysts.
Quinoxalines that have a pyrazine ring fused with a benzene ring are frequently utilized as dyes, antibiotics, and pharmaceuticals like actinoleutin, echinomycin, and levomycin.
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Quinoxalin-6-ylmethanamine hydrochloride
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1-(3-Chloroquinoxalin-2-yl)piperidin-4-ol
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3-(Trifluoromethyl)quinoxalin-2(1H)-one
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Methyl 2,3-dichloroquinoxaline-6-carboxylate