Home Chemistry Heterocyclic Building Blocks Aliphatic Heterocycles 1,4-Diazepan-5-One
Reduction: The carbonyl group in 1,4-diazepan-5-one can be reduced to form the corresponding alcohol using reducing agents such as lithium aluminum hydride (LiAlH4) or sodium borohydride (NaBH4).
Acylation: The nitrogen atom in the diazepine ring can undergo acylation reactions with acyl chlorides or anhydrides, leading to the formation of amides.
Ring Opening: The diazepine ring can undergo ring-opening reactions under specific conditions, yielding open-chain compounds with functional groups at the ring-opening sites.
Condensation Reactions: 1,4-diazepan-5-one can participate in condensation reactions with other compounds containing suitable functional groups, leading to the formation of various heterocyclic compounds.
Substitution Reactions: Substituent groups on the diazepine ring can undergo substitution reactions with nucleophiles or electrophiles, depending on the reaction conditions.
Oxidation: The compound can be oxidized to form a corresponding N-oxide or other oxidation products.
Cyclization Reactions: Depending on the reaction conditions and reagents, 1,4-diazepan-5-one can undergo cyclization reactions to form different heterocyclic compounds.
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tert-Butyl 5-oxo-1,4-diazepane-1-carboxylate
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1-Methyl-1,4-diazepan-5-one hydrochloride
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4-Methyl-1,4-diazepan-5-one hydrochloride
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4-(2-(Dimethylamino)ethyl)-1,4-diazepan-5-one
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